A Study Assessing Patients' Quality of Life and Function after Different Types of Surgery for Cancer in the Femur (Thighbone)


Full Title

A Randomized Trial to Assess Patient Quality of Life and Function after Alternative Surgeries for Pathologic Fractures of the Femur


In this study, researchers are comparing two different surgical approaches regularly used to treat cancer that has spread to and weakened the femur (thighbone). They are looking to see if there are differences after surgery in function, quality of life, pain control, and possible complications in patients who have had these procedures.

Patients in this study will be randomly assigned to one of two surgeries:

  • “Hip, Ball, Rod, and Cement” (long-stem cemented hemiarthroplasty), in which the ball of the hip is replaced with a metal ball, and a rod is placed inside the femur with cement to keep the implant in place.
  • “Rod and Screws” (intramedullary nailing), in which a metal rod is placed inside the femur and secured in place with metal screws just below the hip and above the knee.


To be eligible for this study, patients must meet several criteria, including but not limited to the following:

  • Patients must have cancer that has spread to and weakened the femur.
  • Patients with all cancers are eligible, except for those with lymphoma.
  • Patients with advanced arthritis of the hip may not participate.
  • This study is for patients age 18 and older.

For more information about this study, please contact Dr. John Healey at 212-639-7610.



Disease Status

Relapsed or Refractory