A Study Comparing the Effectiveness of Virtual and Standard Colonoscopy for Colorectal Cancer Follow-up

Full Title

Comparative Effectiveness of Virtual and Optical Colonoscopy for Colorectal Cancer (CRC) Surveillance


The usual follow-up for patients whose colorectal cancer was cured with surgery includes a standard colonoscopy plus a computed tomography (CT) scan of the abdomen and pelvis to look for evidence of cancer outside of the colon. These tests are done one year after surgery. Virtual colonoscopy involves the use of CT imaging to examine the inside of the colon. It is known that a virtual colonoscopy study provides the same information as a standard CT scan. However, doctors do not know if virtual colonoscopy is as effective as standard colonoscopy for monitoring the colon in these patients.

The primary purpose of this study is to determine if virtual colonoscopy is an effective alternative to undergoing the combination of standard colonoscopy plus a CT scan in patients who have had curative surgery for colorectal cancer. Participants will have both the virtual colonoscopy procedure (including the CT scan) and the standard colonoscopy procedure on the same day. (Both require the same bowel-cleansing preparation the day before.) Researchers will compare the test results, and will also ask patients questions about which test they preferred.


This study is open to patients age 18 and older who had surgery that cured their colorectal cancer.

For more information and to inquire about eligibility for this study, please contact Dr. Marc Gollub at 212-639-2183.