Calypso-Based Deep Inspiration Breath Hold Radiation Treatment for Lung Cancer


Full Title

Calypso-based Deep Inspiration Breath Hold (DIBH) Radiation Treatments of Lung Cancer


When radiation therapy is given as a treatment for lung cancer, doctors need to make sure the radiation beams are directed to the tumor and not to nearby healthy tissue. Because the lungs move with breathing during radiation therapy, healthy tissue is at risk of receiving radiation. Patients may be asked to intermittently hold their breath during treatment, but even then, the tumor may be in a slightly different place each time, since each breath hold is different.

The goal of this study is to assess a new approach to determine where a lung tumor is during radiation treatment using special “Calypso beacon” implants. Calypso beacons are small devices implanted in a patient’s lung near the tumor. They send a signal to a tracking system to show where they are and where the tumor is as the patient holds his or her breath during radiation treatment. Doctors will implant two to three small beacons near a patient’s tumor during a bronchoscopy procedure.


To be eligible for this study, patients must meet several criteria, including but not limited to the following:

  • Patients must be candidates for radiation therapy of primary or recurrent lung cancer.
  • Patients must be candidates for bronchoscopy to implant the Calypso beacons.
  • Patients must be able to hold their breath five times for more than 20 seconds each time.
  • This study is for patients age 18 and older.

For more information about this study and to inquire about eligibility, please contact Dr. Andreas Rimner at 646-608-2449.