Full TitleA Prospective Phase II Trial to Evaluate Esophageal Reinforcement with ACell Gentrix Surgical Matrix: a degradable biologic scaffold material
In patients who have had a tumor surgically removed from the esophagus or stomach, a complication may occur at the site where the two ends of the gastrointestinal tract were reconnected (“anastomosis”), causing leakage or a narrowing (“stricture”). About 10 percent of patients experience these complications, extending their hospital stay and often requiring them to have more tests and procedures.
In this study, surgeons are determining if a product called MatriStem can help reduce the risk of these complications when wrapped, like a blanket, around the site of the connection.
To be eligible for this study, patients must meet several criteria, including but not limited to the following:
- Patients must be planning to undergo surgery to remove a tumor of the esophagus, stomach, or junction between the esophagus and stomach that requires a reconnection of two ends of the esophagus.
- Patients with metastatic cancer may not participate.
- This study is open to patients age 18 and older.