A Study Comparing Whole Breast Ultrasound with Contrast-Enhanced Digital Mammography for Breast Cancer Screening

Full Title

Comparison of Whole Breast Screening Ultrasound and Contrast Enhanced Mammography for Supplemental Breast Cancer Screening


Whole breast ultrasound is often used as part of breast cancer screening in women with dense breasts because it has been shown to detect more cancers than regular mammography in these patients. Contrast-enhanced digital mammography is a form of mammography performed after the patient has received an intravenous injection of iodine dye, and has also been shown to detect more breast cancers than standard mammography.

The purpose of this study is to compare the effectiveness of breast ultrasound and contrast-enhanced digital mammography for detecting breast tumors in women already scheduled to have a breast ultrasound and mammogram or a contrast-enhanced digital mammogram. Each participant will have both tests, which will be performed on the same day.


To be eligible for this study, patients must meet several criteria, including but not limited to the following:

  • Participants must be women age 30 and older who are scheduled to have both ultrasound and either standard or contrast-enhanced digital mammography on the same day or within 30 days of each other. Women who are scheduled to have contrast-enhanced mammography alone may also participate.
  • Participants may not have any breast symptoms (such as a palpable mass or nipple discharge), any known breast cancer or a history of breast cancer, a history of breast surgery or biopsy within 90 days of entering the study, or an implant in the breast being imaged. Participants may not have had a breast MRI in the three years prior to entering the study.

For more information and to inquire about eligibility for this study, please contact Dr. Janice Sung at 646-888-5423.



Disease Status

Newly Diagnosed & Relapsed/Refractory