EXCITE: Exercise Intensity Trial to Compare Linear and Nonlinear Exercise Training in Women Treated for Operable Early-Stage Breast Cancer

Full Title

Exercise Intensity Trial (EXCITE): A Randomized Trial Comparing the Effects of Linear Versus Non-Linear Aerobic Training in Women with Operable Breast Cancer


Chemotherapy, radiation therapy, and other treatments for breast cancer can be tiring and reduce a woman’s quality of life. Studies have suggested that exercise can reduce some of these side effects, but research has not been done to compare different exercise approaches. That is the goal of this study.

Participants in this study include women who’ve completed treatment for early-stage breast cancer. First they will undergo testing of their heart and breathing function, body composition, and physical fitness. Then they will be randomly assigned to one of three groups:

  1. Supervised exercise training: Four exercise sessions (walking on a treadmill) each week for 16 weeks, at a moderate level of intensity that does not change.

  2. Supervised exercise training: Four exercise sessions (walking on a treadmill) each week for 16 weeks, at different levels of intensity (low, moderate, and high).

  3. Supervised progressive stretching: Three to four sessions a week for 16 weeks.

Researchers will compare the fitness and cardiovascular test results between the three groups before and after the 16-week study period. Women will also be asked to complete lifestyle questionnaires to evaluate the effects of exercise on their quality of life.


Participants in this study will include postmenopausal women (age 21 and older) who have completed treatment for early-stage breast cancer and are able to come to Memorial Sloan Kettering in Manhattan to complete the exercise/stretching sessions.

For more information about this study and to inquire about eligibility, contact Dr. Lee Jones at 646-888-8102.






Scott, Jessica, PhD