A Study of Treatment-Related Hair, Skin, and Nail Changes Among Women with Non-Metastatic Breast Cancer


Full Title

A Prospective, Longitudinal Study of Chemotherapy-Induced Hair Changes and Alopecia, Skin Aging and Nail Changes in Women with Non-Metastatic Breast Cancer


The purpose of this study is to see how many women develop hair, skin, and nail changes due to breast cancer treatment. The investigators would like to study the clinical factors, genetic markers, and impact of these changes on patients’ health-related quality of life to learn more about who is most at risk. They believe that the study will improve the understanding of how people with cancer feel about their skin, hair, and nail conditions. This information will help doctors learn how to prevent these conditions, and it may improve the way patients are treated and counseled.

This study will also include healthy menopausal women who will answer the questionnaires, and researchers will compare their responses with the patients.


To be eligible for this study, patients must meet several criteria, including but not limited to the following:

  • Patients must be newly diagnosed with stage 0-III breast cancer and be starting chemotherapy or hormonal therapy.
  • Patients may not have prior hair loss (alopecia) and may not have previously undergone radiation therapy to the head or a cosmetic procedure (such as Botox or a face lift).
  • Healthy menopausal women may also participate in this study.
  • Participants must be able to communicate in English and comply with follow-up visits, assessments, and questionnaires at Memorial Sloan Kettering.
  • This study is for women age 18 and older.

For more information about this study, please contact Dr. Mario Lacouture at 646-888-6014.