A Phase I Study of Chemoembolization for Metastatic Tumors in the Lung

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Full Title

Phase I Study of Transarterial Chemoembolization of Lung Metastases

Purpose

Chemoembolization is a procedure that involves injecting chemotherapy directly into an artery that supplies blood to tumors, and then blocking off the blood supply to the tumors. It has been used for years to treat cancer in the liver.

In this study, researchers want to see if it is safe to perform chemoembolization in patients with lung metastases and to see if they can use this technique to deliver chemotherapy to lung tumors successfully. The chemotherapy drug to be used is mitomycin.

Eligibility

To be eligible for this study, patients must meet several criteria, including but not limited to the following:

  • Patients must have metastatic cancer in the lungs, pleura, bronchus, or mediastinum that cannot be successfully treated with chemotherapy, surgery, ablation, or radiation therapy.
  • Patients with cancer that started in the lungs (primary lung cancer) may not participate.
  • Patients must be physically well enough that they are fully ambulatory, capable of all self-care, and capable of all but physically strenuous activities. As an example, patients must be well enough that they would be able to carry out office work or light housework.
  • This study is for patients age 18 and older.

For more information and to inquire about eligibility for this study, please contact Dr. Franz E. Boas at 212-639-2536.

Protocol

19-371

Phase

I

Disease Status

Newly Diagnosed

Investigator