Full TitleA Modular Phase I/IIa, Open-label, Multi-centre Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of Ascending Doses of AZD5305 as Monotherapy and in Combination with Anti-cancer Agents in Patients with Advanced Solid Malignancies (PETRA)
The purpose of this study is to assess the safety and effectiveness of the investigational PARP inhibitor, AZD5305, in patients with advanced solid tumors. AZD5305 is taken orally (by mouth).
Who Can Join
To be eligible for this study, patients must meet several criteria, including but not limited to the following:
- Patients must have an advanced solid tumor that has continued to grow despite treatment.
- Patients should recover from the serious side effects of prior therapies before receiving the study treatment.
- Patients must be able to walk and do routine activities for more than half of their normal waking hours.
- This study is for patients age 18 and older.
For more information about this study and to inquire about eligibility, please contact Dr. Alison Schram at 646-888-5388.