A Study of the NanoKnife System in People with Localized Prostate Cancer


Full Title

Pivotal Study of the NanoKnife System for Ablation of Prostate Tissue in an Intermediate-Risk Patient Population


The purpose of this study is to see if the NanoKnife System is safe and effective for treating prostate cancer that has not spread beyond the prostate. NanoKnife uses electrical pulses to make small holes in cells. By directing those pulses at prostate cancer cells, the NanoKnife System may destroy prostate cancer.

Who Can Join

To be eligible for this study, patients must meet several requirements, including:

  • Participants must have prostate cancer that has not spread beyond the prostate and has not yet been treated with any anticancer therapies.
  • Patients’ cancers must be grade 3+4 or 4+3 and confined to just one side of the prostate.
  • People with active implanted electronic devices, such as a pacemaker, may not participate.
  • This study is for people over age 50.

For more information about this study and to ask about eligibility, please contact the office of Dr. Jonathan Coleman at 646-422-4432.





Disease Status

Relapsed or Refractory


Coleman, Jonathan, MD


ClinicalTrials.gov ID