Medical Oncologist

Head, Division of Solid Tumor Oncology; Winthrop Rockefeller Chair of Medical Oncology

David R. Spriggs, MD -- Head, Division of Solid Tumor Oncology; Winthrop Rockefeller Chair of Medical Oncology

About Me

As a medical oncologist and the leader of Memorial Sloan Kettering’s Division of Solid Tumors, I have two principal responsibilities:  to manage gynecologic malignancies (predominantly ovarian cancers) and to lead our program in early drug development. 

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 A critical role of medical oncologists is to coordinate surgery, radiation oncology treatments, and chemotherapy to help people preserve their quality of life during treatment. Since joining Memorial Sloan Kettering in 1993 I have had the privilege of caring for thousands of patients with solid tumors and finding the management approach that works best for them.

One of the most rewarding parts of my career has been the long-term relationships that I have developed with these individuals and their families. I am also deeply committed to providing continuity of care for my patients, from earliest diagnosis through multiple treatments into the supportive care phase of cancer management. 

For women with early-stage gynecologic cancers, we offer aggressive treatments with the goal of curing the cancer. Managing the toxic effects of these therapies is crucial—but cure is often possible. When a cure is much less likely because the cancer is more advanced, we focus primarily on controlling the cancer and taking steps to preserve the woman’s quality of life. We also offer new, investigational therapies to people with cancer that has recurred (reappeared). 

In addition to the daily care of women  with gynecologic cancers, I run clinical trials that are testing new, targeted drugs, and oversee a small research laboratory looking for answers to such questions as why certain tumors resist drug treatment and how genes can affect the development of tumors.

In my work on a national scale, I serve on committees for the National Cancer Institute and play a role on the editorial boards of such publications as Investigational New Drugs, Gynecologic Oncology, and Clinical Cancer Research. Currently I am the associate editor of the Journal of Clinical Oncology. Over the years, I have authored (or co-authored) more than 150 journal articles on such topics as ovarian cancer biology and the results of clinical investigations, from the earliest stages of drug development to randomized phase III trials.

  • Clinical Expertise: Gynecologic Oncology; Clinical Pharmacology; General Medical Oncology
  • Awards and Honors: New York Magazine Top Doctors (2004-2008; 2010; 2016)
  • Languages Spoken: English
  • Education: MD, University of Wisconsin
  • Residencies: Pathology - New York Hospital; Medicine - Presbyterian Hospital
  • Fellowships: Medicine - Dana Farber Cancer Institute/Brigham and Women's Hospital; Medicine - Harvard Medical School; Medicine - Columbia University
  • Board Certifications: Medical Oncology; Internal Medicine

My Research

View my lab

See David R. Spriggs’ laboratory
research at Memorial Sloan Kettering.


Visit PubMed for a full listing of David R. Spriggs’ journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Clinical Trials

As home to one of the world’s top cancer research centers, Memorial Sloan Kettering is typically involved in more than 900 clinical trials at a given time. Currently, clinical trials focused on the conditions I treat are enrolling new patients. If you’re interested in joining a clinical trial, click to learn about the trial’s purpose, eligibility criteria, and how to get more information.

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Most major health insurers offer plans that include MSK as one of their in-network providers. If MSK is in-network, it means all our doctors are too. Medicaid and New York State Medicare also provide benefits for care at MSK.

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