Govindarajan Srimathveeravalli, PhD

About Me

I am a biomedical engineer with expertise in developing electromechanical systems and medical devices for minimally invasive image-guided interventional therapy. I perform basic and preclinical research to develop solutions that will provide physicians access and the ability to deliver therapy to tumors and pre-cancerous conditions in the genitourinary, gastrointestinal and pulmonary tracts.

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I have an established track record of developing innovative image-guided robotic systems that provide easy access and a high degree of control to the physician performing the procedure. This includes a steering system for the remote control of catheters while performing endovascular procedures and an MRI safe robot for performing targeted prostate biopsies, developed in collaboration with the URobotics Lab at Johns Hopkins University. I have also developed novel medical devices, such as specially designed lumen specific electrode-catheters.

My current research interest focuses on developing an understanding of the subtle biology-dependent differences in the way cancerous and different types of normal cells react to lethal and sub-lethal energies deposited in them during ablations. Particularly, I am investigating cellular response following exposure to pulsed electric fields, commonly used to induce electroporation. Understanding these differences will allow me to develop new ablation techniques that are capable of finely targeting malignant cells while largely sparing non-targeted healthy tissue in the vicinity of the ablation. In turn, this will pave the way for energy parameters to treat tumors in the genitourinary and gastrointestinal tract with minimal risk of perforation or stricture formation.

I have a passion for scientific education. I provide the research fellows and visiting investigators on our service exposure to biomedical engineering, medical device development, and techniques in preclinical research. I also teach a course titled “Principals of Medical Device Design” in the Department of Biomedical Engineering at City College of New York.

  • Clinical Expertise: Imaging Sciences
  • Languages Spoken: English
  • Education: PhD in mechanical engineering, University at Buffalo
  • Fellowships: Memorial Sloan Kettering Cancer Center (radiology)

Appointments Available

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Clinical Trials

As home to one of the world’s top cancer research centers, Memorial Sloan Kettering is typically involved in more than 900 clinical trials at a given time. Currently, clinical trials focused on the conditions I treat are enrolling new patients. If you’re interested in joining a clinical trial, click to learn about the trial’s purpose, eligibility criteria, and how to get more information.

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