Pictured: Jorge Reis-Filho

Jorge S. Reis-Filho, MD, PhD, FRCPath

Surgical Pathologist

Titles

Chief, Experimental Pathology Service

Clinical Expertise

Experimental Pathology; Gene Expression Profiling; Genomics; Breast Cancer

New Patient Appointments

Scheduling a visit is easy. Click below or call us to get started.

Accepted Insurance Providers

Dr. Reis-Filho accepts the following list of insurance providers. Select your insurance provider to see more details.

Contact and Location

Locations map

Find a Convenient Location

Memorial Sloan Kettering has locations throughout New York City, Long Island, New Jersey, and Westchester. These locations offers many services, including screening, chemotherapy, and medical testing.

About Me

Education

MD, Universidade do Porto (Portugal), Universidade Federal do Parana (Curitiba, Brazil); PhD, Universidade do Minho (Braga, Portugal) and The Institute of Cancer Research (London, UK)

Residencies

Universidade Federal do Parana (Curitiba, Brazil)

Fellowships

Institute of Molecular Pathology and Immunology, University of Porto (Portugal); The Institute of Cancer Research, Royal Marsden Hospital (London, UK)

I am a surgical pathologist with experience in breast cancer gene expression profiling and genomics, and in combining traditional pathology information with data generated with high-throughput molecular techniques. The main focus of my research is on rare types of breast cancer, which together account for up to 25 percent of all invasive breast cancers. Unlike the common type of breast cancer, which comprises multiple entities with distinct biological features and clinical behaviors, tumors from each of the rare types have been shown to be relatively homogeneous at the molecular level.

With the recent development of techniques that allow us to survey the entire repertoire of mutations tumor cells harbor, we now have the opportunity to ascertain which alterations drive the growth and ability of these rare types of breast cancer to metastasize, and to define potential therapeutic targets that can be used to manage not only these rare cancers but also subsets of the common types of the disease. Understanding the anatomical and biological characteristics of tumors that govern their outcome and response to specific therapies is germane for the realization of the potentials of personalized medicine.

Our laboratory in the Human Oncology and Pathogenesis Program also focuses on the impact of intra-tumor genetic heterogeneity on the biology and clinical behavior of breast cancers, and on the development of diagnostic, prognostic, and predictive biomarkers. We are currently investigating whether circulating DNA and/or circulating tumor cells can be used to define the constellation of mutations found in primary or metastatic breast cancers and whether the genetic analyses of these biological materials would complement the analysis of the primary tumor for clinical decision-making.

Memorial Sloan Kettering Cancer Center provides an optimal environment for me to pursue these research aims, given its collegial and collaborative environment, the well-characterized institutional collections of rare tumor types, and state-of-the-art research facilities.

Over the past seven years, I have lectured at various national and international conferences, and mentored PhD and MD students. I am the recipient of the 2007 CL Oakley Lectureship by the Pathological Society of Great Britain and Ireland, the British Association for Cancer Research 2007 Translational Research Award, the 2010 Ramzi Cotran Young Investigator Award by the United States and Canadian Academy of Pathology, and the 2010 Future Leaders Prize by Cancer Research UK. I am the youngest-ever Fellow of The Royal College of Pathologists to have become a member by published works. I am the international editor of Advances in Anatomical Pathology, an associate editor of The Journal of Pathology and BMC Cancer, a member of the scientific advisory board of Science Translational Medicine, and a member of the editorial board of Laboratory Investigation and Modern Pathology.

Colleagues

Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.

Clinical Trials

Smiling doctors in the lab

Find a Clinical Trial for You

Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.

You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.

Research and Publications

View Dr. Reis-Filho's Lab

Publications on PubMed

Visit PubMed for a full listing of Dr. Reis-Filho’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.