I have been a practicing interventional radiologist for 24 years. As an interventional radiologist, I use imaging guidance to perform in a “minimally invasive” manner procedures that might otherwise be performed surgically. There is no need for general anesthesia, no incision, and only a short recovery time.
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I am known locally and nationally for my expertise in image-guided biopsy, an outpatient procedure that allows for rapid diagnosis of a tumor and then initiation of treatment. Virtually any tumor within the chest, abdomen, or pelvis can be biopsied safely with a needle using imaging guidance, thus avoiding general anesthesia and complications associated with traditional surgical biopsy. This is often a patient’s first experience with an interventional radiologist.
I am also recognized for expertise in both the diagnosis and minimally invasive management of primary and secondary liver tumors, with emphasis on hepatocellular cancer (hepatoma) and metastatic neuroendocrine tumors. To this end, I work very closely with a team of hepatobiliary surgeons, gastrointestinal oncologists, and gastroenterologists in order to determine the most appropriate treatment for each patient. Cancer within the liver can be treated using embolization, in which the blood supply to a tumor (or tumors) within the liver is “shut off.” Since 1992, I have worked to refine this technique, and I have published data supporting this method of treatment. I am the Primary Investigator on an NIH funded trial comparing results of embolization with particles alone to embolization performed with particles loaded with chemotherapy.
Thermal ablative techniques (such as radiofrequency ablation and cryoablation) can also be used to treat tumors, not only within the liver but also within the lung, kidney, and bone. These techniques involve inserting a needle-like “probe” into a tumor using imaging guidance. The “probe” then heats or freezes the tumor, resulting in thermal-mediated tumor cell death. The object of this type of procedure is to kill the tumor while preserving the surrounding normal tissue.
Although I have published papers, spoken nationally, and taught courses on these topics, caring for patients is still my primary focus. I have been chosen one of New York’s Top Doctors on six occasions since 2003. My goal each day is not only to perform procedures safely, efficiently, and with technical expertise, but also to provide the best experience possible for our patients.
- Clinical Expertise: Vascular and Interventional Radiology
- Awards and Honors: Castle Connolly: New York Magazine Top Doctors (2003, 2005-2012, 2016-2017); Castle Connolly: America's Top Doctors (2016-2018)
- Languages Spoken: English
- Education: MD, Boston University School of Medicine
- Residencies: Massachusetts General Hospital
- Fellowships: Massachusetts General Hospital
- Board Certifications: Diagnostic Radiology; CAQ in Interventional Radiology
Research is integral to our mission at Memorial Sloan Kettering, and clinical trials help us discover better forms of patient care and treatment. For you, this could mean access to a new therapy or therapy combination. Click to see a list of the trials I’m currently leading.
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Clinical Trials Co-Investigated by Karen T. Brown
Most major health insurers offer plans that include MSK as one of their in-network providers. If MSK is in-network, it means all our doctors are too. Medicaid and New York State Medicare also provide benefits for care at MSK.Learn more