Lillian M. Smyth, MD

About Me

I am a medical oncologist who cares for women with breast cancer. I work closely with a team of surgeons, oncologists, and radiation therapists to provide patients with personalized treatment plans and am committed to delivering exceptional, compassionate care to my patients.

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My clinical research focuses on developing new treatments for breast cancer. I specialize in early-phase cancer clinical trials, called phase I trials. In these trials, patients receive new cancer medicines or new combinations of cancer medicines for the first time. I am particularly interested in developing new therapies that target the molecular changes that drive cancer. My translational research with liquid and tumor biopsies focuses on identifying and understanding the biomarkers of response or resistance to these targeted therapies.

  • Clinical Expertise: Breast Cancer; Early Phase Clinical Trials
  • Awards and Honors: Irish Society of Medical Oncology Scholarship award (2012); American Society of Clinical Oncology (ASCO) Merit Award (2015 & 2016); ASCO Young Investigator Award (2016)
  • Languages Spoken: English
  • Education: MBBCh BAO, University College Dublin
  • Residencies: Internal Medicine - Royal College of Physicians Ireland
  • Fellowships: Medical Oncology - Mater Misericordiae University Hospital; Medical Oncology - Royal College of Physicians Ireland; Medical Oncology - Memorial Sloan Kettering Cancer Center

New Patient Appointments

Making an appointment

Call 646-497-9064


Visit PubMed for a full listing of Lillian M. Smyth’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Clinical Trials

Research is integral to our mission at Memorial Sloan Kettering, and clinical trials help us discover better forms of patient care and treatment. For you, this could mean access to a new therapy or therapy combination. Click to see a list of the trials I’m currently leading.

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Most major health insurers offer plans that include MSK as one of their in-network providers. If MSK is in-network, it means all our doctors are too. Medicaid and New York State Medicare also provide benefits for care at MSK.

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