About Me

I provide comprehensive evaluation and management for patients with a variety of pulmonary diseases, in particular patients with cancer, critically ill patients, and those with undiagnosed lung diseases. I am part of a group of physicians with unique expertise in preventing, screening for, diagnosing, and treating lung diseases in ways that give our patients the best possible prognosis. I provide state-of-the-art clinical evaluation, diagnosis, and treatment to patients with common respiratory diseases as well.

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My clinical interests include chemotherapy-induced lung injury, pulmonary complications associated with bone marrow transplantation, chronic obstructive pulmonary disease, interstitial lung diseases, and acute respiratory failure in the immunocompromised patient. Sleep disorders are extremely common in patients with cancer. As a physician who is board certified in sleep medicine, I have the opportunity to evaluate and manage sleep disturbances including sleep apnea, insomnia, and other sleep-related breathing problems such as management of CPAP, BiPAP adjustment difficulties, and more.

At MSK, patient care and research are closely integrated to provide the best care possible for our patients, as well as to advance the science of pulmonary, critical care, and sleep medicine. I have published a number of abstracts and articles in high-profile peer-reviewed journals and have written numerous textbook chapters. I have also presented at local and national conferences and conducted research on a number of the topics.

  • Clinical Expertise: Pulmonary disorders in cancer patients; pulmonary complications due to chemotherapeutic drugs; pulmonary manifestation in bone marrow transplant and hematological malignancy; interstitial lung disease; autoimmune lung diseases; chronic obstructive pulmonary disease; chronic respiratory failure; weaning from mechanical ventilation; asthma; general pulmonary diseases; sleep-related breathing disorders; sleep disorders associated with cancer and cancer treatment
  • Languages Spoken: English
  • Education: MD, University of the State of New York; MBBS, University of Kerala
  • Residencies: Case Western Reserve University
  • Fellowships: National Jewish Health/ University of Colorado; Mount Sinai St. Luke’s and Roosevelt Hospitals
  • Board Certifications: Internal Medicine; Pulmonary Disease; Sleep Medicine; Critical Care Medicine

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Geraghty P., Eden E., Pillai M., Campos M., McElvaney N.G., Foronjy R.F.” α1-Antitrypsin Activates Protein Phosphatase 2A to Counter Lung Inflammatory Responses “, Am J Respir Crit Care Med., Vol. 190, Issue 11 (December 1, 2014), pp. 1229-1242. PMID: 25341065 doi:10.1164/rccm.201405-0872OC

Pillai M., Olson A.L., Huie T.J., Solomon J.J., Fernandez-Perez E.R., Brown K.K., Hanna P., Lee-Chiong T., Swigris J.J. “Obstructive sleep apnea does not promote esophageal reflux in fibrosing interstitial lung disease”. Respir Med. 2012 July; 106(7): 1033–1039. PMID: 22521226 PMCID: PMC3362045 NIHMSID: NIHMS372264 doi:10.1016/j.rmed.2012.03.014. [Support Funding: NIH (K23 HL092227)]

Morjaria S, Otto C, Moreira A, Chung R, Hatzoglou V, Pillai M, Banaei N, Tang YW, Figueroa CJ “Ribosomal RNA gene sequencing for early diagnosis of Blastomyces dermatitidis infection”. Int J Infect Dis. 2015 Aug; 37:122-4. doi: 10.1016/j.ijid.2015.06.017. Epub 2015 Jun 28.

Garcia-Arcos I., Cummings N., Dabo A.J., Pillai M.V., Geraghty P., Goldberg I.J., Foronjy R.F. ‘Low density lipoprotein related protein 1 regulates lung inflammation’. (Pulmonary Basic Science Research). Accepted at: Experimental Biology Annual Meeting (EB 2014), April 26-30, 2014, San Diego, CA. FASEB J April 2014 28:609.9 [Grant Funding Source: Supported by NIH 5R01HL098528-05]

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Pillai M.V., Garcia-Arcos I., Dabo A.J., Geraghty P., Foronjy R.F. ‘Involvement of Tumor Necrosis Factor Receptors 1 and 2 (TNFR1 and TNFR2) on Protein Phosphatase 2A (PP2A) Activation in the Lung’. (Pulmonary Basic Science Research). Accepted at: American Thoracic Society (ATS) International Conference, May 16-21, 2014; San Diego, CA

Geraghty P., Eden E., Pillai M.V., Campos M., McElvaney N.G., Foronjy R.F. ‘Alpha-1 antitrypsin counters inflammation by modulating the activity of protein phosphatase 2A’. (Pulmonary Basic Science Research). Accepted at: American Thoracic Society (ATS) International Conference, May 16-21, 2014; San Diego, CA

Shah A., Pillai M.V., Gandhi U., Eden E., Shapiro J. ‘New-Onset Atrial Fibrillation/Atrial Flutter in Medical Intensive Care Unit (MICU) Patients with Severe Sepsis Is Associated With Stroke and Increased Mortality’. Accepted at: American Thoracic Society (ATS) International Conference, May 16-21, 2014; San Diego, CA

Pillai M.V., Ohleyer V., Powers R., Collazo M., Jean R., Shapiro J. ‘Implementation of a Collaborative Weaning Protocol for Acute and Chronic Respiratory Failure in Critical Care’. Accepted at: American Thoracic Society (ATS) International Conference, May 16-21, 2014; San Diego, CA

Aguirre H., Jivraj A., Mains S., Tartell L., Pillai M.V., Eden E. ‘Reasons Preventing COPD Patients From Completing Pulmonary Rehabilitation’. Accepted at: American Thoracic Society (ATS) International Conference, May 16-21, 2014; San Diego, CA

Pillai M., Oonwala A., Narayanswami G. ‘Point of care ultrasonography leading to the diagnosis of pneumatosis intestinalis’. Presented at: American College of Chest Physicians (CHEST) Annual Meeting 2013, October 26–31; Chicago, IL

Pillai M.V., Killam J., Legasto A.C., Eden E., Tartell L., Minkin R. ‘Prediction and Grading Of Pulmonary Hypertension Severity with Computerized Tomography’. Presented at: American Thoracic Society (ATS) International Conference, May 17-22, 2013; Philadelphia, PA

Pillai M., Lee-Chiong T., Hanna P., Swigris J.J. ‘Obstructive Sleep Apnea (OSA) and Gastroesophageal Reflux Disease (GERD) Are Common in Patients with Fibrotic Interstitial Lung Disease (Fild)’. Presented at: American College of Chest Physicians (CHEST) Annual Meeting 2011, October 22-26; Honolulu, Hawaii

Harrington J., Pillai M., Lee-Chiong T., Goelz K., Aloia M.S. ‘Retrospective Perception of Subjective Sleepiness Predicts Adherence to Positive Airway Pressure’. Presented at: American Academy of Sleep Medicine (AASM), Sleep 2011 25th Anniversary meeting, June 11-15, 2011; Minneapolis, MN

Pillai M.V., Iqbal S., Merugu S., Sopko J. ‘In Hospital Use Of Berlin Questionnaire, Nocturnal Pulse Oximetry And Continuous Positive Airway Pressure Trial Response To Desaturation Are As Accurate As Polysomnography In Diagnosing Obstructive Sleep Apnea’. Presented at: American Thoracic Society (ATS) International Conference, May 13-18, 2011; Denver, CO

Khatri S.B., Newman C., Rose J., Ross K.R., Pillai M., Holstein A., Tailor S., Hammond D., Norris G. ‘Associations Of Air Quality With Asthma During The Cleveland Multiple Air Pollutant Study’. Presented at: American Thoracic Society (ATS) International Conference, May 14-19, 2010; New Orleans, LA. Funded by: U.S. EPA, NIH CTSC Pilot Award UL1-RR024989

Alraiyes A.H., Pillai M., Alhindi S., Alokla K., Sopko J. ‘Application of the Review of Systems (ROS) Protocol in the ICU and its effect on the length and cost of stay and outcome’ (Critical Care Medicine 2008 Vol. 36, No. 12, A96 (Suppl)). Presented at: 38th Critical Care Congress, Nashville, TN, January 31 - February 4, 2009, Society of Critical Care Medicine (SCCM); Nashville, TN

Visit PubMed for a full listing of Manju V. Pillai’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Clinical Trials

As home to one of the world’s top cancer research centers, Memorial Sloan Kettering is typically involved in more than 900 clinical trials at a given time. Currently, clinical trials focused on the conditions I treat are enrolling new patients. If you’re interested in joining a clinical trial, click to learn about the trial’s purpose, eligibility criteria, and how to get more information.

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Most major health insurers offer plans that include MSK as one of their in-network providers. If MSK is in-network, it means all our doctors are too. Medicaid and New York State Medicare also provide benefits for care at MSK.

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