Mary L. Gemignani, MD, MPH, FACS

About Me

I am a surgeon who specializes in the diagnosis and treatment of breast cancer. I joined Memorial Sloan Kettering in 1996 and completed fellowships in both breast surgery and gynecologic oncology. I have been practicing at MSK ever since. My dual training, research interests, and experience make me uniquely suited to provide expert care for women with hereditary breast cancer. This includes doing risk-reducing double mastectomies for women with BRCA mutations or other familial risks.

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I perform about 300 procedures each year and see patients at MSK’s Breast and Imaging Center in Manhattan. My goal is not only to provide advanced surgical techniques, but also to bring together a team of superb colleagues in medical oncology, radiation oncology, and plastic surgery. We then make a comprehensive treatment plan tailored to each individual patient.

From early on in medical school, I knew that I wanted to dedicate my career to women’s health and oncology. I provide care that takes into account quality of life concerns for women with breast cancer, including cosmetic outcomes. When appropriate, I offer cosmetic options such as nipple sparing mastectomy and aim to minimize the side effects of breast cancer surgery. It’s my goal to help my patients get back to their lives as quickly as possible after surgery.

My current research interest is in patient-reported outcomes, which involves studying symptoms and side effects after surgery directly from the patient’s perspective. This information is vital for finding ways to improve the surgical experience for our patients. I am also studying how best to address the fertility concerns of young women who have been diagnosed with breast cancer.

I am the Director of MSK’s Breast Surgical Fellowship Training Program and responsible for the educational training program for a highly selected group of surgeons choosing to specialize in breast surgery. I am an active member of local, national, and international societies. These include the American College of Surgeons, the Society of Surgical Oncology, the American Society of Breast Surgeons, and the American Society of Clinical Oncology.

As a surgeon, I aim to provide hope and support as women with cancer navigate one of the most difficult times in their lives. At the end of a consultation, I want each of my patients to feel that they have the information they need to make decisions about their treatment. I want them to have less fear about their diagnosis and to know that I will be with them to help and guide them through their journey.

Outside of work, I am an avid runner, and I enjoy spending time with my family.

  • Clinical Expertise: Breast Cancer
  • Languages Spoken: English
  • Education: MD, Mount Sinai School of Medicine; MPH, Mailman School of Public Health, Columbia University
  • Residencies: Obstetrics and Gynecology - SUNY Health Science Center at Brooklyn
  • Fellowships: Gynecologic Oncology - Memorial Sloan Kettering Cancer Center; Breast Surgery - Memorial Sloan Kettering Cancer Center
  • Board Certifications: Gynecologic Oncology; Fellowship certification Breast Surgery

See My Colleagues


Visit PubMed for a full listing of Mary L. Gemignani’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Clinical Trials

As home to one of the world’s top cancer research centers, Memorial Sloan Kettering is typically involved in more than 900 clinical trials at a given time. Currently, clinical trials focused on the conditions I treat are enrolling new patients. If you’re interested in joining a clinical trial, click to learn about the trial’s purpose, eligibility criteria, and how to get more information.

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Most major health insurers offer plans that include MSK as one of their in-network providers. If MSK is in-network, it means all our doctors are too. Medicaid and New York State Medicare also provide benefits for care at MSK.

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