Memorial Sloan Kettering breast surgeon Melissa Pilewskie

Melissa L. Pilewskie, MD, FACS



Director, Strategic Planning and Research, RISE Program

Clinical Expertise

Breast Disease; Lumpectomy; Mastectomy; Nipple-Sparing Mastectomy; Axillary Lymph Node Procedures

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Accepted Insurance Providers

Dr. Pilewskie accepts the following list of insurance providers. Select your insurance provider to see more details.

Contact and Location

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Find a Convenient Location

Memorial Sloan Kettering has locations throughout New York City, Long Island, New Jersey, and Westchester. These locations offers many services, including screening, chemotherapy, and medical testing.

About Me


MD, Ohio State University


General Surgery - Northwestern University


Breast Surgery - Memorial Sloan Kettering Cancer Center

Board Certifications

General Surgery

I am a surgical breast oncologist whose practice is dedicated to the treatment of breast diseases. I strive to always give my patients compassionate care, both in the clinic and in the operating room, where I perform all aspects of breast cancer surgery, including breast conservation (lumpectomy), mastectomy, nipple-sparing mastectomy, and axillary lymph node procedures. I see patients at the Evelyn H. Lauder Breast Center in Manhattan and at MSK Bergen, in New Jersey. 

In addition to my clinical practice, I am actively involved in research that aims to continuously improve the care of our breast cancer patients. Some of my previous research has included work on the utilization of breast MRI for women with both invasive and in situ carcinoma and the appropriate surgical treatment for triple-negative breast cancers. 

Currently, I am engaged in research to help personalize screening recommendations for women at high of developing breast cancer, working closely with MSK’s RISE program (Risk assessment, Imaging, Surveillance, and Education). My hope is that my research will enable us to deliver more individualized patient care and screening recommendations in the future. While many women in the RISE program do not require surgery, I counsel and treat women with high-risk breast lesions that do require excision, such as atypical ductal hyperplasia. I also work with many young women who have a genetic predisposition to breast cancer and are interested in undergoing bilateral prophylactic mastectomies for risk reduction. 

Furthermore, I continue to study the appropriate management of ductal carcinoma in situ (DCIS), otherwise known as stage 0 breast cancer. DCIS is currently a controversial topic in medicine. I have worked with my colleagues to assess the risk of finding invasive cancer when surgery is performed for DCIS and to help predict the risk of a recurrence following our standard therapies. Our goal is to better define women with low-risk DCIS who may not require all aspects of breast cancer care. In addition, I am studying novel therapies such as topical medicine and exercise that may provide nontoxic treatment options for patients with DCIS or elevated breast cancer risk.


Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. I work closely with nurse practitioner Margot LeStrange. We combine our expertise to provide comprehensive care to our patients at every step of their cancer journey.

Clinical Trials

Smiling doctors in the lab

Find a Clinical Trial for You

Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.

You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.

Research and Publications

Publications on PubMed

Visit PubMed for a full listing of Dr. Pilewskie’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.