Memorial Sloan Kettering radiation oncologist Samuel Bakhoum

Samuel F. Bakhoum, MD, PhD

Radiation Oncologist

Clinical Expertise

Breast Cancer

New Patient Appointments

Scheduling a visit is easy. Click below or call us to get started.

Accepted Insurance Providers

Dr. Bakhoum accepts the following list of insurance providers. Select your insurance provider to see more details.

Contact and Location

Locations map

Find a Convenient Location

Memorial Sloan Kettering has locations throughout New York City, Long Island, New Jersey, and Westchester. These locations offers many services, including screening, chemotherapy, and medical testing.

About Me


MD, Dartmouth Medical School; PhD, Dartmouth College


Radiation Oncology - Memorial Sloan Kettering Cancer Center

I am a radiation oncologist who specializes in caring for people with breast cancer. My practice is located at Memorial Hospital in Manhattan. I am also a researcher who is working to understand more about how cancer grows and spreads. Ultimately, my goal is for this knowledge to help develop more effective treatments for our patients.

Being a cancer doctor at MSK means I have the opportunity to be a member of a team that draws on a wide range of expertise from a variety of disciplines. I also have the privilege of connecting with my patients and their families on many levels. This includes caring for their emotional well-being while using the most cutting-edge scientific knowledge to guide their treatment. Each person I care for is unique and deserves a personalized treatment plan for their specific needs.

In addition, I conduct research into how cancer can change its genetic makeup to evade treatments and spread to distant organs. One genetic error that has been linked to cancer aggressiveness and resistance to treatment is called chromosomal instability (CIN). My lab is dedicated to learning about CIN and using this information for therapies that tackle aggressive cancers and their ability to spread.

When I meet with my patients, I hope they leave with a sense of control and confidence in the treatment we have carefully planned for them. By having a full understanding of all the options available, patients can overcome the emotional challenges of a cancer diagnosis and feel positive and hopeful about their treatment outcome.

Each person I care for is unique and deserves a personalized treatment plan for their specific needs.

Dr. Bakhoum

Awards and Honors

  • Josie Robertson Investigator (2018-2023)
  • Blavatnik Regional Awards for Young Scientists, Finalist (2018)
  • Tri-Institutional Breakout Prize (2018)
  • Burroughs Wellcome Fund Career Award for Medical Scientists (2018)
  • NextGen Stars, American Association for Cancer Research (2018)
  • Breast Cancer Breakthrough Award, Department of Defense (2016)
  • ASCI/AAP Outstanding Young Investigator Award (2011)
  • Norton B. Gilula Award, the American Society for Cell Biology (2008)


Doctors at Memorial Sloan Kettering work as teams, with specialists from all different areas. This allows us to consider all your needs together, and to give you the best possible care.

Clinical Trials

Smiling doctors in the lab

Find a Clinical Trial for You

Memorial Sloan Kettering's doctors and scientists are constantly developing new treatments for cancer. MSK is typically running hundreds of clinical trials at a given time.

You may be able to participate in a clinical trial even if you are new to MSK. Search our online directory to find trial information and see more about who can participate.

Research and Publications

View Dr. Bakhoum's Lab

Bakhoum SF (corresponding author), Cantley LC (2018) The multifaceted role of chromosomal instability in cancer and its microenvironment. Cell: 174: 1347-1360

Bakhoum SF*, Ngo B*, Laughney AM, Cavallo JA, Murphy CJ, Ly P, Shah P, Sriram RK, Watkins TBK, Taunk NK, Duran M, Pauli C, Shaw C, Chadalavada K, Rajasekhar VK, Genovese G, Venkatesan S, BirkBak NJ, McGranahan N, Lundquist M, Laplant Q, Healy JH, Elemento O, Chung CH, Lee NY, Imielenski M, Nanjangud G, Pe’er D, Cleveland D, Powell SN, Lammerding J, Swanton C, Cantley LC (2018) Chromosomal Instability drives metastasis through a cytosolic DNA response. Nature: 553, 467-472. PMID: 29342134

Laughney AM, Elizalde S, Genovese G, Bakhoum SF (corresponding author) (2015) Dynamics of tumor heterogeneity derived from clonal karyotypic evolution. Cell Reports: 12, 809-820. PMID: 26212324

Bakhoum SF (corresponding author), Kabeche L, Wood MD, Laucius CD, Qu D, Laughney AM, Louie RJ, Phillips J, Chan DA, Petritsch C, Zaki BI, Murnane JP, Compton DA (2015) Numerical chromosomal instability mediates susceptibility to radiation treatment. Nature Communications: 6, 5990. PMID: 25606712

Publications on PubMed

Visit PubMed for a full listing of Dr. Bakhoum’s journal articles. Pubmed is an online index of research papers and other articles from the US National Library of Medicine and the National Institutes of Health.