About Me

I am a radiation and cell biologist working in the Radiochemistry and Imaging Sciences Service within Memorial Sloan Kettering’s Department of Radiology. My major interest is the development and evaluation of new radioactive compounds for use in cancer imaging and therapy. I am also interested in identifying new ways to use these compounds for diagnosis, treatment, and monitoring cancer therapy. To do this, we use a combination of biological imaging and nuclear imaging techniques. These techniques allow us to directly compare the location of the radioactive compound with various biological characteristics of the tumor. We perform these comparisons at both the macroscopic and the microscopic levels to help our understanding of how the radiotracers behave and what that reveals about the cancer.

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This type of work is a strong collaborative effort and depends upon contributions from scientists with many different backgrounds. I have been very fortunate to have the opportunity to build such collaborations and am grateful for the outstanding research environment that Memorial Sloan Kettering’s Department of Radiology provides.

My current research interests include development and evaluation of PET hypoxia tracers uing small molecules and antibodies specific for cellular proteins induced by hypoxia; the use of PET hypoxia tracers to indicate response following treatments argeted at tomor vasculature; the development of novel cell-based model systems for the investigation of tumor behavior and tracer validation; the use of combined magnetic resonance and PET imaging techniques to help define radiotracer behavior.

  • Clinical Expertise: Evaluation of radiotracer uptake and distribution in biopsy and surgical material
  • Languages Spoken: English
  • Education: PhD, Radiopharmacology, University of Glasgow (Scotland)
  • Fellowships: American Cancer Society Fellowship at Duke University

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Visit PubMed for a full listing of Sean D. Carlin’s journal articles

Pubmed is an online index of biomedical articles maintained by the U.S. National Library of Medicine and the National Institutes of Health.

Clinical Trials

As home to one of the world’s top cancer research centers, Memorial Sloan Kettering is typically involved in more than 900 clinical trials at a given time. Currently, clinical trials focused on the conditions I treat are enrolling new patients. If you’re interested in joining a clinical trial, click to learn about the trial’s purpose, eligibility criteria, and how to get more information.

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