Yingbei Chen, MD, PhD

About Me

  • Clinical Expertise: Genitourinary Pathology
  • Languages Spoken: English
  • Education: MD, Peking Union Medical College (China); PhD, The Johns Hopkins School of Medicine
  • Residencies: NewYork-Presbyterian Hospital/Weill Cornell Medical Center
  • Fellowships: The Johns Hopkins Hospital
  • Board Certifications: Anatomic and Clinical Pathology

Appointments Available

Making an appointment

Call 800-525-2225
Mon–Fri, 8:30 AM–5:30 PM, ET

See My Colleagues


Chen YB, Aon MA, Hsu YT, Soane L, Teng X, McCaffery JM, Cheng WC, Qi B, Li H, Alavian KN, Dayhoff-Brannigan M, Zou S, Pineda FJ, O’Rourke B, Ko YH, Pedersen PL, Kaczmarek LK, Jonas EA, Hardwick JM. Bcl-xlL regulates mitochondrial energetics by stabilizing the inner membrane potential. Journal of Cell Biology 2011; 195(2):263-76.

Alavian KN, Li H, Collis L, Bonanni L, Zeng L, Sacchetti S, Lazrove E, Nabili P, Flaherty B, Graham M, Chen YB, Messerli SM, Mariggio MA, Rahner C, McNay E, Shore GC, Smith PJ, Hardwick JM, Jonas EA.  Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FoATP synthase. Nature Cell Biology 2011; 13(10):1224-33.

Chen YB, Fine SW, Epstein JI. Mesonephric Remnant Hyperplasia Involving Prostate and Periprostatic Tissue: Findings at Radical Prostatectomy. American Journal of Surgical Pathology 2011; 35(7):1054-61.

Przybycin CG, Cronin AM, Darvishian F, Gopalan A, Al-Ahmadie HA, Fine SW, Chen YB, Bernstein M, Russo P, Reuter VE, Tickoo SK. Chromophobe Renal Cell Carcinoma: A Clinicopathologic Study of 203 Tumors in 200 Patients With Primary Resection at a Single Institution. American Journal of Surgical Pathology 2011; 35(7):962-70.

Al-Ahmadie HA, Iyer G, Janakiraman M, Lin O, Heguy A, Tickoo SK, Fine SW, Gopalan A, Chen YB, Balar A, Riches J, Bochner B, Dalbagni G, Bajorin DF, Reuter VE, Milowsky MI, Solit DB.  Somatic mutation of fibroblast growth factor receptor-3 (FGFR3) defines a distinct morphological subtype of high-grade urothelial carcinoma. Journal of Pathology 2011; 224(2):270-9.

Chen YB, Epstein JI. Primary carcinoid tumors of the urinary bladder and prostatic urethra: a clinicopathologic study of 6 cases. American Journal of Surgical lPathology 2011; 35(3):442-6.

Schultz L, Albadine R, Hicks J, Jadallah S, DeMarzo AM, Chen YB, Neilsen ME, Gonzalgo ML, Sidransky D, Schoenberg M, Netto GJ. Expression status and prognostic significance of mammalian target of rapamycin pathway members in urothelial carcinoma of urinary bladder after cystectomy. Cancer 2010; 116(23):5517-26.

Rickman DS*, Chen YB*, Banerjee S, Pan Y, Yu J, Vuong T, Perner S, Lafargue CJ, Mertz KD, Setlur SR, Sircar K, Chinnaiyan AM, Bismar TA, Rubin MA, Demichelis F. ERG cooperates with androgen receptor in regulating trefiol factor 3 in prostate cancer disease progression. Neoplasia 2010; 12(12):1031-40 (*equal contribution).

Chen YB, Pierorazio PM, Epstein JI. Initial atypical diagnosis with carcinoma on subsequent prostate needle biopsy: findings at radical prostatectomy. Journal of Urology 2010; 184(5):1953-7.

Palanisamy N, Ateeq B, Kalyana-Sundaram S, Pflueger D, Ramnarayanan K, Shankar S, Han B, Cao Q, Cao X, Suleman K, Kumar-Sinha C, Dhanasekaran SM, Chen YB, Esgueva R, Banerjee S, LaFargue CJ, Siddiqui J, Demichelis F, Moeller P, Bismar TA, Kuefer R, Fullen. Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma. Nature Medicine 2010; 16(7) :7793-8

Miller JS, Chen YB, Ye H, Robinson BD, Brimo F and Epstein JI. Extraprostatic extension of prostatic adenocarcinoma on needle core biopsy: repoprt of 72 case with clinical follow-up. BJU International 2010; 106(3):330-3.

Berman SB, Chen YB, Qi B, McCaffery JM, Rucker EB 3rd, Goebbels S, Nave KA, Arnold BA, Jonas EA, Pineda FJ, Hardwick JM. Bcl-x L increases mitochondrial fission, fusion, and biomass in neurons. Journal of Cell Biology 2009; 184(5) :707-19

Read more

Chen YB, Tu JJ, Kao J, Zhou XK, Chen YT.. Survivin as a useful adjunct marker for the grading of papillary urothelial carcinoma. Archives of Pathology and Laboratory Medicine 2008; 132(2) :224-31

Chen YB, Magpayo J, Rosen PP.. Sclerosing adenosis in sentinel axillary lymph nodes from a patient with invasive ductal carcinoma: an unusual variant of benign glandular inclusions. Archives of Pathology and Laboratory Medicine 2008; 132(9) :1439-41

Li H, Chen Y, Jones AF, Sanger RH, Collis LP, Flannery R, McNay EC, Yu T, Schwarzenbacher R, Bossy B, Bossy-Wetzel E, Bennett MV, Pypaert M, Hickman JA, Smith PJ, Hardwick JM, Jonas EA.. Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons. PNAS 2008; 105(6) :2169-74

Wurmbach E, Chen YB, Khitrov G, Zhang W, Roayaie S, Schwartz M, Fiel I, Thung S, Mazzaferro V, Bruix J, Bottinger E, Friedman S, Waxman S, Llovet JM.. Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma.. Hepatology 2007; 45(4) :938-47

Chen YB, Seo SY, Kirsch DG, Sheu TT, Cheng WC, Hardwick JM.. Alternate functions of viral regulators of cell death. Cell Death Differentiation 2006; 13(8) :1318-24

Llovet JM, Chen Y, Wurmbach E, Roayaie S, Fiel MI, Schwartz M, Thung SN, Khitrov G, Zhang W, Villanueva A, Battiston C, Mazzaferro V, Bruix J, Waxman S, Friedman SL.. A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis. Gastroenterology 2006; 131(6) :1758-67

Zhang J, Chen YB, Hardwick JM, Miller MI, Plachez C, Richards LJ, Yarowsky P, van Zijl P, Mori S.. Magnetic resonance diffusion tensor microimaging reveals a role for Bcl-x in brain development and homeostasis.. Journal Of Neuroscience 2005; 25(8) :1881-8

Seo SY, Chen YB, Ivanovska I, Ranger AM, Hong SJ, Dawson VL, Korsmeyer SJ, Bellows DS, Fannjiang Y, Hardwick JM.. BAD is a pro-survival factor prior to activation of its pro-apoptotic function. Journal of Biological Chemistry 2004; 279(40) :42240-9

Clinical Trials

Research is integral to our mission at Memorial Sloan Kettering, and clinical trials help us discover better forms of patient care and treatment. For you, this could mean access to a new therapy or therapy combination. Click to see a list of the trials I’m currently leading.