Lumizyme; Myozyme [DSC]
- Very bad and sometimes life-threatening allergic reactions have happened with this drug. These reactions have happened during infusion and up to 3 hours after it is done.
- Very bad reactions like kidney problems and skin reactions have happened after treatment with this drug. These reactions have happened several weeks to 3 years after treatment started. Talk with the doctor.
- During or after the infusion, tell the doctor if your child has back pain; bluish skin or nails; a burning, numbness, or tingling feeling that is not normal; chest pain; dizziness or passing out; fast or trouble breathing; fast or slow heartbeat; feeling hot or cold; feeling nervous or restless; fever or chills; flushing; headache; hives; itching; pale skin; rash; seizures; sweating more than normal; swelling; tightness in the chest or throat; upset stomach; or wheezing.
- Your child will be closely watched by the doctor.
- Tell the doctor if your child has any heart or lung problems. If your child has a reaction to this drug, the heart or lung problem may get worse. Talk with the doctor.
- It is used to treat Pompe disease.
- If your child has an allergy to this drug or any part of this drug.
- If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
If your child is breast-feeding a baby:
- Be sure your child does not breast-feed a baby for 24 hours after getting this drug.
- Tell all of your child’s health care providers that your child is taking this drug. This includes your child’s doctors, nurses, pharmacists, and dentists.
- If your child will be getting anesthesia, talk with the doctor. The chance of a heartbeat that is not normal and sudden death from heart problems may be raised in some people.
- Have your child’s blood work checked often. Talk with your child’s doctor.
- Have your child’s urine checked as you have been told by the doctor.
If your child is pregnant:
- Tell the doctor if your child is pregnant or becomes pregnant. You will need to talk about the benefits and risks of your child using this drug while pregnant.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
- Shortness of breath, a big weight gain, or swelling in the arms or legs.
- Feeling agitated.
- Muscle pain.
- A heartbeat that does not feel normal.
- Feeling very tired or weak.
- Irritation where the shot is given.
- It is given as an infusion into a vein over a period of time.
- Call your child’s doctor to find out what to do.
- If you need to store this drug at home, talk with your doctor, nurse, or pharmacist about how to store it.
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
- Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.