- This drug may cause a very bad and sometimes deadly type of heartbeat that is not normal (long QT on ECG, torsades de pointes). The chance may be raised if your child takes amphotericin B or some types of water pills (diuretics), if your child has low potassium or magnesium levels, or if your child has heart failure. The chance may also be raised if your child has ever had a long QT on ECG or torsades de pointes. Talk with the doctor.
- Talk with the doctor if your child is taking any drugs that can cause a certain type of heartbeat that is not normal (prolonged QT interval). There are many drugs that can do this. Ask the doctor or pharmacist if you are not sure.
- Your child will need an ECG before starting this drug and during treatment. Talk with the doctor.
- Your child will need blood work checked before starting this drug and during treatment. Talk with the doctor.
- This drug may cause a very bad and sometimes deadly health problem called retinoic-acid-APL syndrome. Call the doctor right away if your child has a fever, shortness of breath or trouble breathing, or sudden weight gain.
- It is used to treat a type of leukemia.
- It may be given to your child for other reasons. Talk with the doctor.
- If your child has an allergy to this drug or any part of this drug.
- If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- Tell dentists, surgeons, and other doctors that your child is using this drug.
- Your child may have more chance of getting infections. Avoid crowds and people with infections, colds, or flu.
- Your child may bleed more easily. Make sure your child is careful and avoids injury. Be sure your child has a soft toothbrush.
- This drug may add to the chance of getting some types of cancer. Talk with the doctor.
- If your child has an upset stomach or loose stools (diarrhea), is throwing up, or is not hungry, talk with the doctor. There may be ways to lower these side effects.
- If your child has high blood sugar (diabetes), talk with the doctor. This drug can raise blood sugar.
- Have your child’s blood sugar checked as you have been told by your child’s doctor.
If your child is or may be sexually active:
- Have your child use birth control to prevent pregnancy during care and for some time after care ends. Talk with the doctor to see how long your child needs to use birth control after stopping this drug.
- If your child is a male and has sex with a female who could get pregnant, they must prevent pregnancy during care and for some time after care ends. Talk with the doctor to see how long they must use birth control after your child stops this drug.
If your child is pregnant or breast-feeding a baby:
- This drug may cause harm to the unborn baby if your child takes it during pregnancy. If your child is pregnant or gets pregnant while taking this drug, call the doctor right away.
- Tell the doctor if your child is breast-feeding a baby. You will need to talk about any risks to the baby.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
- Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
- Signs of low potassium levels like muscle pain or weakness, muscle cramps, or a heartbeat that does not feel normal.
- Chest pain or pressure or a fast heartbeat.
- A heartbeat that does not feel normal.
- Very bad dizziness or passing out.
- Very bad headache.
- Feeling very tired or weak.
- Low mood (depression).
- A burning, numbness, or tingling feeling that is not normal.
- Blurred eyesight.
- Upset stomach or throwing up.
- Belly pain.
- Hard stools (constipation).
- Loose stools (diarrhea).
- Not hungry.
- Weight gain.
- Feeling tired or weak.
- Not able to sleep.
- Bone, joint, or muscle pain.
- Back pain.
- Sweating a lot.
- Pain where the shot was given.
- Redness or swelling where the shot is given.
- Eye irritation.
- Pain in arms or legs.
- Dry skin.
- Neck pain.
- Pale skin.
- Skin irritation.
- It is given as an infusion into a vein over a period of time.
- Call the doctor to find out what to do.
- This drug will be given to your child in a hospital or doctor’s office. You will not store it at home.
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
- Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call
Arsenic Trioxide©2015 Memorial Sloan Kettering Cancer Center - Generated on July 3, 2015