Atazanavir

Pediatric Medication

Brand Names: US

Reyataz

Brand Names: Canada

Reyataz

What is this drug used for?

  • It is used to treat HIV infection.

What do I need to tell the doctor BEFORE my child takes this drug?

All products:

  • If your child has an allergy to any part of this drug.
  • If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If your child has any of these health problems: Kidney disease or liver disease.
  • If your child takes any drugs (prescription or OTC, natural products, vitamins) that must not be taken with this drug, like certain drugs that are used for high cholesterol, migraines, or mood problems. There are many drugs that must not be taken with this drug.
  • If your child is taking St. John’s wort. Do not give St. John’s wort with this drug. This drug may not work as well.

If your child is breast-feeding a baby:

  • Be sure your child does not breast-feed a baby while taking this drug.

Capsules:

  • If the patient is a child who weighs less than 33 lb (15 kg).

Powder for suspension:

  • If the patient is a child who weighs less than 11 lb (5 kg) or is younger than 3 months of age.
This is not a list of all drugs or health problems that interact with this drug.
Tell the doctor and pharmacist about all of your child’s drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for your child to take this drug with all of his/her drugs and health problems. Do not start, stop, or change the dose of any drug your child takes without checking with the doctor.

What are some things I need to know or do while my child takes this drug?

All products:

  • Tell all of your child’s health care providers that your child is taking this drug. This includes your child’s doctors, nurses, pharmacists, and dentists.
  • This drug interacts with many other drugs. The chance of this drug’s side effects may be raised or how well this drug works may be lowered. The chance of the other drugs’ side effects may also be raised. This may include very bad, life-threatening, or deadly side effects. Check with the doctor and pharmacist to make sure that it is safe for your child to take this drug with all of their other drugs (prescription or OTC, natural products, vitamins).
  • High blood sugar has happened with this drug. This includes diabetes that is new or worse. Talk with the doctor.
  • Have your child’s blood sugar checked as you have been told by your child’s doctor.
  • Some people with hemophilia have had times of more bleeding when taking drugs like this one. If your child has hemophilia, talk with the doctor.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • Have your child’s urine checked as you have been told by the doctor.
  • This drug is not a cure for HIV. Be sure your child stays under the care of the doctor.
  • This drug does not stop the spread of diseases like HIV or hepatitis that are passed through blood. Be sure needles and other things like toothbrushes or razors are not shared. Talk with the doctor.
  • Do not switch between different forms of this drug without first talking with the doctor.
  • This drug may be used with other drugs to treat your child’s health condition. If your child is also taking other drugs, talk with your child’s doctor about the risks and side effects that may happen.

If your child is or may be sexually active:

  • This drug does not stop the spread of diseases like HIV or hepatitis that are passed through having sex. Be sure your child does not have any kind of sex without using a latex or polyurethane condom. Talk with the doctor.
  • Birth control pills and other hormone-based birth control may not work as well to prevent pregnancy. Be sure your child uses some other kind of birth control also, like a condom, when taking this drug.

If your child is pregnant:

  • Tell the doctor if your child is pregnant or becomes pregnant. You will need to talk about the benefits and risks of your child using this drug while pregnant.
  • If your child used this drug when she was pregnant, tell the doctor if the baby has yellow skin or eyes after the baby is born.

Powder for suspension:

  • If your child has phenylketonuria (PKU), talk with your child’s doctor. Some products have phenylalanine.

What are some side effects that I need to call my child’s doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child’s doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
  • Signs of gallstones like sudden pain in the upper right belly area, right shoulder area, or between the shoulder blades; yellow skin or eyes; or fever with chills.
  • Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
  • A heartbeat that does not feel normal.
  • Dizziness or passing out.
  • Muscle or joint pain.
  • Pain when passing urine.
  • Back pain, belly pain, or blood in the urine. May be signs of a kidney stone.
  • A burning, numbness, or tingling feeling that is not normal.
  • Low mood (depression).
  • Any unexplained bruising or bleeding.
  • Change in body fat.
  • Yellow skin or eyes.
  • Swelling in the arms or legs.
  • A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if your child has signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in the mouth, throat, nose, or eyes.
  • Changes in your child’s immune system can happen when your child starts taking drugs to treat HIV. If your child has an infection that you did not know was there, it may show up when your child takes this drug. Tell your child’s doctor right away if your child has any new signs after starting this drug, even after taking it for several months. This includes signs of infection like fever, sore throat, weakness, cough, or shortness of breath.
  • If your child has liver problems like hepatitis B or C, talk with your child’s doctor. Liver problems have gotten worse with this drug. Call your child’s doctor right away if your child has signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child’s doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away:
  • Headache.
  • Loose stools (diarrhea).
  • Belly pain.
  • Upset stomach or throwing up.
  • Not able to sleep.
  • Nose or throat irritation.
These are not all of the side effects that may occur. If you have questions about side effects, call your child’s doctor. Call your child’s doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best given?

Give this drug as ordered by your child’s doctor. Read all information given to you. Follow all instructions closely.

All products:

  • Give this drug with food.
  • Do not give antacids to your child within 1 hour before or 2 hours after giving this drug.
  • If your child is also taking didanosine, give it at least 1 hour before or 2 hours after this drug.
  • If your child takes cimetidine, dexlansoprazole, esomeprazole, famotidine, lansoprazole, nizatidine, omeprazole, pantoprazole, rabeprazole, or ranitidine, ask your child’s doctor or pharmacist how to give it with this drug.
  • Keep giving this drug to your child as you have been told by your child’s doctor or other health care provider, even if your child feels well.
  • It is important that your child does not miss or skip a dose of this drug during treatment.
  • Have your child drink lots of noncaffeine liquids every day unless told to drink less liquid by your child’s doctor.

Capsules:

  • Have your child swallow whole. Do not let your child chew, open, or crush.
  • If your child has trouble swallowing, talk with the doctor.

Powder for suspension:

  • This drug must be mixed before using. Mix the powder with soft food like applesauce or yogurt. If you cannot do this, mix with a drink like milk, infant formula, or water. Mix this drug as the doctor has told you or read the package insert.
  • Give this drug within 1 hour of mixing.
  • This drug must be taken with another drug called ritonavir.

Infants:

  • If you use infant formula to mix the powder, give the drug using an oral dosing syringe. Do not give using an infant bottle.

What do I do if my child misses a dose?

  • Give a missed dose as soon as you think about it, with food.
  • If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
  • Do not give 2 doses at the same time or extra doses.
  • If you are not sure what to do if you miss giving your child a dose, call the doctor.

How do I store and/or throw out this drug?

All products:

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Capsules:

  • Keep lid tightly closed.

Powder for suspension:

  • Store in original container.
  • Do not open until you are ready to use.

General drug facts

  • If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
  • Do not share your child’s drug with others and do not give anyone else’s drug to your child.
  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
  • Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Last Reviewed Date

2018-05-01

Copyright

© 2018 Wolters Kluwer Clinical Drug Information, Inc. and its affiliates and/or licensors. All rights reserved.

Last Updated