Budesonide (Topical)

Adult Medication

Brand Names: US


Brand Names: Canada

Entocort Enema

What is this drug used for?

  • It is used to treat ulcerative colitis.
  • It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take this drug?

All products:

  • If you have an allergy to this drug or any part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have any other bowel problems.
  • If you have an infection.
  • If you have TB (tuberculosis), talk with your doctor.
  • If you have a herpes infection of the eye.
  • If you are taking any of these drugs: Cyclosporine, erythromycin, indinavir, itraconazole, ketoconazole, ritonavir, or saquinavir.

Rectal enema:

  • If you have psychosis.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

  • Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
  • If you have high blood sugar (diabetes), talk with your doctor. This drug may raise blood sugar.
  • Check your blood sugar as you have been told by your doctor.
  • Have a bone density test as you have been told by your doctor. Talk with your doctor.
  • Have your eye pressure checked if you are on this drug for a long time. Talk with your doctor.
  • Talk with your doctor if you come into contact with anyone who has chickenpox or measles and you have not had chickenpox, measles, or the vaccines for them.
  • Avoid grapefruit and grapefruit juice.
  • When changing from an oral steroid to another form of a steroid, there may be very bad and sometimes deadly side effects. Signs like weakness, feeling tired, dizziness, upset stomach, throwing up, not thinking clearly, or low blood sugar may happen. Call your doctor right away if you have any of these signs. If you have a bad injury, have surgery, or any type of infection, you may need extra doses of oral steroids. These extra steroids will help your body deal with these stresses. Carry a warning card saying that there may be times when you may need extra steroids.
  • This drug may affect growth in children and teens in some cases. They may need regular growth checks. Talk with the doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
  • Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
  • Skin changes (pimples, stretch marks, slow healing, hair growth).
  • A fatty pad or hump between the shoulders.
  • Round face.
  • Swelling of the ankles.
  • Feeling very tired or weak.
  • Dizziness or passing out.
  • Very upset stomach or throwing up.
  • Any unexplained bruising or bleeding.
  • Change in eyesight.
  • Bone or joint pain.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

All products:

  • Upset stomach.

Rectal enema:

  • Gas.
  • Loose stools (diarrhea).
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.

All products:

  • To gain the most benefit, do not miss doses.
  • Keep using this drug as you have been told by your doctor or other health care provider, even if you feel well.
  • This drug is for rectal use only. Do not take this drug by mouth.

Rectal foam:

  • Before using this drug, use the bathroom to empty your bowels.
  • Warm the can before use by holding it in your hands and shaking it for 10 to 15 seconds.
  • If you need more lubricant for the applicator, you may use petrolatum or petroleum jelly.
  • You can use this drug while standing, lying down, or sitting.
  • If you are using this drug in the evening, use right before bedtime. After using this drug, try to avoid emptying your bowels until the next morning.
  • This drug may catch on fire. Do not use near an open flame or while smoking.

Rectal enema:

  • This drug needs to be mixed before use. Follow how to mix as you were told by the doctor.
  • Follow how to use as you have been told by the doctor or read the package insert.

What do I do if I miss a dose?

Rectal foam:

  • Use a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.

Rectal enema:

  • Skip the missed dose and go back to your normal time.

All products:

  • Do not use 2 doses or extra doses.

How do I store and/or throw out this drug?

Rectal foam:

  • Store at room temperature. Do not refrigerate or freeze.
  • Protect from light.
  • Protect from heat or open flame. Do not puncture or burn even if it seems empty.

Rectal enema:

  • Store at room temperature.

All products:

  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

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