Chloromycetin®; Chloromycetin® Succinate; Diochloram®; Pentamycetin®
- Very bad and sometimes deadly blood problems have happened with this drug. This may cause more chance of getting an infection, bleeding problems, or slow healing. Aplastic anemia that happened with this drug has led to a certain kind of cancer (leukemia). Blood problems have happened after both short-term use and long-term use. Have your blood work checked while taking this drug. Talk with your doctor.
- It is used to treat bacterial infections.
- If you have an allergy to chloramphenicol or any other part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have any of these health problems: Bone marrow disease or low blood cell counts.
- If you are taking any drugs that can raise the chance of blood problems. There are many drugs that can do this. Ask your doctor or pharmacist if you are not sure.
- Tell dentists, surgeons, and other doctors that you use this drug.
- Do not use longer than you have been told. A second infection may happen.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Very bad dizziness or passing out.
- Feeling very tired or weak.
- Any bruising or bleeding.
- Change in thinking clearly and with logic.
- Mood changes.
- Change in eyesight.
- A burning, numbness, or tingling feeling that is not normal.
- It is common to have diarrhea when taking this drug. Rarely, a very bad form of diarrhea called Clostridium difficile (C diff)–associated diarrhea (CDAD) may occur. Sometimes, this has led to a deadly bowel problem (colitis). CDAD may happen while you are taking this drug or within a few months after you stop taking it. Call your doctor right away if you have stomach pain or cramps, very loose or watery stools, or bloody stools. Do not try to treat loose stools without first checking with your doctor.
- Very bad and sometimes deadly reactions have happened in premature and newborn babies. This has happened in a baby born to a mother who got this drug during labor. It has also happened in a 3-month old. Most of the time, this drug was used within the first 48 hours of life. Signs first show up after 3 to 4 days of getting this drug. Call your child’s doctor right away if your child has swelling of the stomach with or without throwing up, blue or gray skin color, or trouble breathing.
- It is given as a shot into a vein.
- Your doctor may teach you how to give the shot.
- Follow how to use carefully.
- Do not use if the solution is cloudy, leaking, or has particles.
- Do not use if solution changes color.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- Most of the time, this drug will be given in a hospital or doctor’s office. If stored at home, follow how to store as you were told by the doctor.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call
Chloramphenicol©2015 Memorial Sloan Kettering Cancer Center - Generated on October 10, 2015