- It is used to treat soft, brittle bones (osteoporosis).
- It is used for bone growth.
- It is used when treating some cancers.
- It is used to treat high calcium levels in patients with cancer.
- It may be given to you for other reasons. Talk with the doctor.
- If you have an allergy to denosumab or any other part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have low calcium levels.
- If you are pregnant or may be pregnant. Do not take this drug if you are pregnant.
- Tell dentists, surgeons, and other doctors that you use this drug.
- This drug may raise the chance of a broken leg. Talk with the doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Have a bone density test. Talk with your doctor.
- Take calcium and vitamin D as you were told by your doctor.
- Have a dental exam before starting this drug.
- Take good care of your teeth. See a dentist often.
- If you smoke, talk with your doctor.
- Do not give to a child. Talk with your doctor.
- If you are a man and your sex partner is pregnant or gets pregnant at any time while you are being treated, talk with your doctor.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
- Use birth control you can trust to prevent pregnancy while you are taking this drug and for 5 months after you stop taking it.
- This drug may cause harm to the unborn baby if you take it while you are pregnant.
- If you get pregnant while taking this drug or within 5 months after your last dose, call your doctor right away.
- Very bad infections have been reported with use of this drug. If you have any infection, are taking antibiotics now or in the recent past, or have many infections, talk with your doctor.
- You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
- This drug may lower blood calcium levels. If you already have low blood calcium, it may get worse with this drug. Sometimes, blood calcium levels have stayed low for weeks or months after use of this drug. Talk with the doctor.
- Use birth control that you can trust to prevent pregnancy while taking this drug.
- If you get pregnant while taking this drug, call your doctor right away.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of low calcium levels like muscle cramps or spasms, numbness and tingling, or seizures.
- Mouth sores.
- Swelling in the arms or legs.
- Feeling very tired or weak.
- Any new or strange groin, hip, or thigh pain.
- Very bad bone, joint, or muscle pain.
- This drug may cause jawbone problems. The chance may be higher the longer you take this drug. The chance may be higher if you have cancer, dental problems, dentures that do not fit well, anemia, blood clotting problems, or an infection. The chance may also be higher if you are having dental work, getting chemo or radiation, or taking other drugs that may cause jawbone problems like some steroid drugs. There are many drugs that can do this. Ask your doctor or pharmacist if you are not sure. Call your doctor right away if you have jaw swelling or pain.
- Muscle pain or weakness.
- Shortness of breath.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
- Chest pain.
- A heartbeat that does not feel normal.
- Very bad skin irritation.
- Bladder pain or pain when passing urine or change in how much urine is passed.
- Passing urine more often.
- Back pain.
- Hard stools (constipation).
- Not hungry.
- Joint pain.
- Feeling tired or weak.
- Upset stomach or throwing up.
- Loose stools (diarrhea).
- Muscle or joint pain.
- Sore throat.
- Runny nose.
- Pain in arms or legs.
- It is given as a shot into the fatty part of the skin.
- Call the doctor to find out what to do.
- This drug will be given to you in a hospital or doctor’s office. You will not store it at home.
- This drug will be given in a hospital or doctor’s office. If stored at home, follow how to store as you were told by the doctor or pharmacist.
- Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call
Denosumab©2015 Memorial Sloan Kettering Cancer Center - Generated on August 1, 2015