- It is used to treat HIV infection.
- If you have an allergy to efavirenz or any other part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have had red, blistered, swollen, or peeling skin after taking efavirenz.
- If you have liver disease.
- If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with this drug, like certain drugs that are used for hepatitis C, HIV, or infections. There are many drugs that must not be taken with this drug.
- If you are taking another drug that has the same drug in it.
For all patients taking this drug:
- Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how this drug affects you.
- Do not run out of this drug.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This drug may affect certain lab tests. Tell all of your health care providers and lab workers that you take this drug.
- Talk with your doctor before you drink alcohol or use other drugs and natural products that slow your actions.
- This drug is not a cure for HIV. Stay under the care of your doctor.
- This drug does not stop the spread of diseases like HIV or hepatitis that are passed through blood or having sex. Do not have any kind of sex without using a latex or polyurethane condom. Do not share needles or other things like toothbrushes or razors. Talk with your doctor.
- This drug interacts with many other drugs. The chance of this drug’s side effects may be raised or how well this drug works may be lowered. The chance of the other drugs’ side effects may also be raised. This may include very bad, life-threatening, or deadly side effects. Check with your doctor and pharmacist to make sure that it is safe for you to take this drug with all of your other drugs (prescription or OTC, natural products, vitamins).
- This drug may raise the chance of seizures in some people, including people who have had seizures in the past. Talk to your doctor to see if you have a greater chance of seizures while taking this drug.
- This drug may cause high cholesterol and triglyceride levels. Talk with the doctor.
- A type of abnormal heartbeat (prolonged QT interval) can happen with this drug. Call your doctor right away if you have a fast heartbeat, a heartbeat that does not feel normal, or if you pass out.
- If you are able to get pregnant, a pregnancy test will be done to show that you are NOT pregnant before starting this drug. Talk with your doctor.
- This drug may cause harm to the unborn baby if you take it while you are pregnant.
- Use birth control that you can trust to prevent pregnancy while taking this drug and for 3 months after care ends.
- Birth control pills and other hormone-based birth control may not work as well to prevent pregnancy. Use some other kind of birth control also like a condom when taking this drug and for 3 months after your last dose.
- If you get pregnant while taking this drug or within 3 months after your last dose, call your doctor right away.
- Do not breast-feed if you have HIV disease unless your doctor tells you to.
- If your child’s weight changes, talk with the doctor. The dose of this drug may need to be changed.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of low mood (depression), thoughts of killing yourself, nervousness, emotional ups and downs, thinking that is not normal, anxiety, or lack of interest in life.
- Change in body fat.
- Change in the way you act.
- Hallucinations (seeing or hearing things that are not there).
- Memory problems or loss.
- Feeling confused.
- Very bad dizziness or passing out.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
- This drug may help the immune system work. If you have an infection that you did not know you had, it may show up when you take this drug. Tell your doctor right away if you notice any signs of infection like fever, sore throat, weakness, cough, or shortness of breath after you start this drug.
- Very bad and sometimes deadly liver problems have happened with this drug. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Upset stomach or throwing up.
- Loose stools (diarrhea).
- Feeling tired or weak.
- This drug may cause you to have dizziness, sleepiness, trouble sleeping, trouble focusing, or dreams that are not normal. Most of the time, these effects go away after taking this drug for 2 to 4 weeks. It may help if you take this drug at bedtime. If you feel dizzy or sleepy, or you have trouble focusing, avoid driving and doing other tasks or actions that call for you to be alert. Call your doctor if these effects last, they bother you, or are very bad.
- Take this drug at bedtime.
- Take on an empty stomach.
- Take with a full glass of water.
- Swallow whole. Do not chew or crush.
- It is important that you do not miss or skip a dose of this drug during treatment.
- Keep taking this drug as you have been told by your doctor or other health care provider, even if you feel well.
- Do not split or break tablet.
- If you have trouble swallowing, talk with your doctor.
- You may sprinkle contents of capsule on soft food like applesauce or yogurt as you were told by your doctor. Swallow within 30 minutes of mixing. Do not eat any more food for 2 hours after you take your dose.
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- If you are not sure what to do if you miss a dose, call your doctor.
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.