- People with high hemoglobin levels had a higher chance of blood clots, like heart attack and stroke, and death with this drug. Talk with the doctor.
- People with some types of cancer have died sooner when using this drug. This drug also raised the chance of tumor growth and the tumor happening again in these people. Talk with the doctor.
- The doctor will need to watch your child’s blood cell counts and follow your child closely to change the dose to match the body’s needs. Talk with the doctor.
- Cancer patients can only get this drug if doctors or hospitals are in the ESA APPRISE Oncology Program.
- If your child will be having surgery, talk with the doctor. Your child may need to take another drug to keep from getting blood clots while getting this drug.
- It is used to treat anemia.
- It is used to help avoid the need for blood transfusions.
- It may be given to your child for other reasons. Talk with the doctor.
- If your child has an allergy to this drug or any part of this drug.
- If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If your child has very high blood pressure.
- If your child has a kind of anemia called Pure Red Cell Aplasia (PRCA).
- Do not give this drug to a newborn. It has benzyl alcohol.
- If your child is pregnant or breast-feeding a baby. Be sure your child does not take this drug if she is pregnant or breast-feeding a baby.
- Tell dentists, surgeons, and other doctors that your child is using this drug.
- This drug is made from human plasma (part of the blood) and may have viruses that may cause disease. This drug is screened, tested, and treated to lower the chance that it carries an infection. Talk with the doctor.
- Have your child’s blood pressure checked often. Talk with your child’s doctor.
- Have your child’s blood work checked often. Talk with your child’s doctor.
If your child is pregnant or breast-feeding a baby:
- Talk with the doctor if your child is pregnant, becomes pregnant, or is breast-feeding a baby. You will need to talk about the benefits and risks of using this drug.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Chest pain or pressure or a fast heartbeat.
- A heartbeat that does not feel normal.
- Shortness of breath, a big weight gain, swelling in the arms or legs.
- Change in strength on 1 side is greater than the other, trouble speaking or thinking, change in balance, or blurred eyesight.
- Very bad dizziness or passing out.
- Very bad headache.
- Swelling, warmth, numbness, change of color, or pain in a leg or arm.
- Feeling very tired or weak.
- Pale skin.
- Coughing up blood.
- Trouble walking.
- Change in balance.
- Irritation where the shot is given.
- Upset stomach or throwing up.
- Bone, joint, or muscle pain.
- Muscle spasm.
- Mouth irritation or mouth sores.
- Weight loss.
- Not able to sleep.
- Give as you have been told, even if your child feels well.
- To gain the most benefit, do not miss giving your child doses.
- It is given as a shot into the fatty part of the skin.
- This drug may be given as a shot into a vein.
- Your child’s doctor may teach you how to give the shot.
- Follow how to give closely if you are giving the shot at home.
- Do not shake the solution.
- Wash your hands before and after use.
- Do not use if the solution is cloudy, leaking, or has particles.
- Do not use if solution changes color.
- Do not use if it has been frozen.
- Do not give into red or irritated skin.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
- Give a missed dose as soon as you think about it.
- If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
- Do not give 2 doses at the same time or extra doses.
- Store in a refrigerator. Do not freeze.
- Protect from light.
- Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- Throw away any part not used after use.
- Throw away any part not used after 3 weeks.
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
- Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call 212-639-2000.