This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.
- It is used to treat high blood pressure in the lungs.
- If you have an allergy to epoprostenol or any other part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have heart failure (weak heart).
- If you have ever gotten fluid in the lungs with use of this drug.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
- Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how this drug affects you.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
- Have your blood pressure checked often. Talk with your doctor.
- Do not stop taking this drug all of a sudden without calling your doctor. Signs of high pressure in the lungs like shortness of breath, dizziness, or weakness may get worse. Talk with your doctor.
- Always have a backup system close by in case you need to use it.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Shortness of breath.
- Very bad dizziness or passing out.
- Very bad headache.
- Dark urine.
- Chest pain or pressure or a fast heartbeat.
- Slow heartbeat.
- A heartbeat that does not feel normal.
- Pale skin.
- Trouble controlling body movements.
- Feeling very tired or weak.
- A burning, numbness, or tingling feeling that is not normal.
- Swelling of belly.
- Redness or swelling where the shot is given.
- Skin sores.
- Very bad irritation where the shot was given.
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Back pain.
- Irritation where the shot is given.
- Not hungry.
- Jaw pain.
- Bone, joint, or muscle pain.
- Upset stomach or throwing up.
- Flu-like signs. These include headache, weakness, fever, shakes, aches, pains, and sweating.
- Feeling nervous and excitable.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.
Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given into the vein nonstop.
- It is likely that treatment will be needed for a long time, maybe years. You will need to closely follow how to use this drug and how to care for the catheter and infusion pump. Talk with the doctor if you have questions.
- Your doctor may teach you how to give this drug.
- Follow how to use as you have been told by the doctor or read the package insert.
- Wash your hands before and after use.
- Do not use if the solution is cloudy, leaking, or has particles.
- Do not use if solution changes color.
- Be sure you know what types of materials and tubing to use with this drug. If you are not sure, talk with the doctor or pharmacist.
- It is important that the infusion does not stop unless your doctor tells you otherwise. If you miss a dose or if the infusion stops, get medical help right away.
- Store as you have been told by the doctor.
- After opening or mixing this drug with fluids, be sure you know how to store this drug and how long the drug is good for.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.
© 2019 Wolters Kluwer Clinical Drug Information, Inc. and its affiliates and/or licensors. All rights reserved.