Erythromycin (Systemic)

Pediatric Medication

Brand Names: US

E.E.S. 400; E.E.S. Granules; Ery-Tab; EryPed 200; EryPed 400; Erythrocin Lactobionate; Erythrocin Stearate; PCE

Brand Names: Canada

Apo-Erythro Base; Apo-Erythro E-C; Apo-Erythro-ES; Apo-Erythro-S; EES; Erybid; Eryc; Novo-Rythro Estolate; Novo-Rythro Ethylsuccinate; Nu-Erythromycin-S; PCE

What is this drug used for?

  • It is used to treat or prevent bacterial infections.
  • It may be given to your child for other reasons. Talk with the doctor.

What do I need to tell the doctor BEFORE my child takes this drug?

  • If your child has an allergy to this drug or any part of this drug.
  • If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If your child has any of these health problems: Long QT on ECG, low magnesium levels, low potassium levels, or slow heartbeat.
  • If your child takes any drugs (prescription or OTC, natural products, vitamins) that must not be taken with this drug, like certain drugs that are used for mood problems, a heartbeat that is not normal, or migraine headaches. There are many drugs that must not be taken with this drug.
This is not a list of all drugs or health problems that interact with this drug.
Tell the doctor and pharmacist about all of your child’s drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for your child to take this drug with all of his/her drugs and health problems. Do not start, stop, or change the dose of any drug your child takes without checking with the doctor.

What are some things I need to know or do while my child takes this drug?

  • Tell dentists, surgeons, and other doctors that your child is using this drug.
  • Have your child’s blood work checked if he/she is on this drug for a long time. Talk with your child’s doctor.
  • This drug may affect certain lab tests. Be sure the doctor and lab workers know your child takes this drug.
  • Do not give to your child longer than you have been told. A second infection may happen.
  • If your child is on a low-salt or salt-free diet, talk with your child’s doctor.

If your child is pregnant or breast-feeding a baby:

  • Talk with the doctor if your child is pregnant, becomes pregnant, or is breast-feeding a baby. You will need to talk about the benefits and risks of using this drug.

What are some side effects that I need to call my child’s doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child’s doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
  • Very upset stomach or throwing up.
  • Not able to pass urine or change in how much urine is passed.
  • Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
  • Seizures.
  • A very bad and sometimes deadly type of heartbeat that is not normal (long QT on ECG) has happened with this drug. Some other drugs taken along with this drug may add to this effect. Get medical help right away if your child’s heartbeat does not feel normal.
  • A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if your child has signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in the mouth, throat, nose, or eyes.
  • It is common to have loose stools (diarrhea) when taking this drug. Rarely, a very bad and sometimes deadly form of loose stools may occur (pseudomembranous colitis). This may happen while your child is taking this drug or within a few months after he/she stops taking it. Call your child’s doctor right away if your child has stomach pain or cramps, very loose or watery stools, or bloody stools. Do not try to treat loose stools without first checking with the doctor.
  • Hearing loss has rarely happened in people taking this drug. This most often goes back to normal. The chance may be higher if your child has kidney problems or takes high doses of this drug. Call the doctor right away if your child has hearing problems like hearing loss.
  • If your child has myasthenia gravis, talk with the doctor. Call the doctor if your child’s signs get worse. Signs of myasthenia gravis have also happened in people who do not have it. Call the doctor right away if your child has new or worse muscle weakness, trouble chewing or swallowing, trouble breathing, droopy eyelids, or change in eyesight like blurred eyesight or seeing double.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child’s doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away:

All products:

  • Belly pain.
  • Upset stomach or throwing up.
  • Loose stools (diarrhea).
  • Not hungry.

Shot:

  • Irritation where the shot is given.
These are not all of the side effects that may occur. If you have questions about side effects, call your child’s doctor. Call your child’s doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best given?

Give this drug as ordered by your child’s doctor. Read all information given to you. Follow all instructions closely.

All products:

  • To gain the most benefit, do not miss giving your child doses.
  • Give as you have been told, even if your child feels well.
  • Give this drug at the same time of day.

Oral:

  • Give this drug with or without food. Give with food if it causes an upset stomach.

Long-acting tablets:

  • Have your child swallow whole. Do not let your child chew, break, or crush.

Liquid (suspension):

  • Shake well before use.
  • Measure liquid doses carefully. Use the measuring device that comes with this drug. If there is none, get an oral syringe, a dropper, a spoon, or a cup (only for older children) from your pharmacist.

Shot:

  • It is given as a shot into a vein.
  • Your child’s doctor may teach you how to give the shot.
  • Follow how to give this drug as you have been told by your child’s doctor.
  • Do not use if the solution is cloudy, leaking, or has particles.
  • Do not use if solution changes color.
  • Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.

What do I do if my child misses a dose?

  • Give a missed dose as soon as you think about it.
  • If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
  • Do not give 2 doses or extra doses.

How do I store and/or throw out this drug?

Tablets and capsules:

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.

Liquid (suspension):

  • Some brands of this drug need to be stored in a refrigerator. Some brands of this drug need to be stored at room temperature. If you have questions about how to store this drug, talk with your pharmacist.

Shot:

  • Most of the time, this drug will be given in a hospital or doctor’s office. If stored at home, follow how to store as you were told by the doctor.

All products:

  • Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
  • Do not share your child’s drug with others and do not give anyone else’s drug to your child.
  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
  • Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Last Reviewed Date

2015-03-18

Copyright

© 2015 Wolters Kluwer Clinical Drug Information, Inc. and its affiliates and/or licensors. All rights reserved.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call 212-639-2000.
Erythromycin (Systemic)
©2015 Memorial Sloan Kettering Cancer Center - Generated on July 29, 2015