Esomeprazole

Pediatric Medication

Brand Names: US

NexIUM; Nexium 24HR [OTC]; NexIUM I.V.

Brand Names: Canada

Apo-Esomeprazole; Mylan-Esomeprazole; Nexium; PMS-Esomeprazole DR

What is this drug used for?

  • It is used to treat gastroesophageal reflux disease.
  • It is used to treat or prevent GI (gastrointestinal) ulcers caused by infection.
  • It is used to treat or prevent ulcers of the swallowing tube (esophagus).
  • It is used to treat syndromes caused by lots of stomach acid.
  • It is used to treat or prevent NSAID-associated gastric ulcers in patients with a history of ulcers.
  • It is used to treat heartburn.
  • It may be given to your child for other reasons. Talk with the doctor.

What do I need to tell the doctor BEFORE my child takes this drug?

All products:

  • If your child has an allergy to esomeprazole or any other part of this drug.
  • If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If your child is taking any of these drugs: Atazanavir, clopidogrel, nelfinavir, rifampin, or St. John’s wort.

Nexium 24HR:

  • If your child has any of these health problems: Black or bloody stools; heartburn with lightheadedness, sweating, or dizziness; chest pain; shoulder pain with shortness of breath; pain that spreads to the arms, neck, or shoulders; lightheadedness; sweating a lot; throwing up blood; or trouble or pain swallowing food.
This is not a list of all drugs or health problems that interact with this drug.
Tell the doctor and pharmacist about all of your child’s drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for your child to take this drug with all of their drugs and health problems. Do not start, stop, or change the dose of any drug your child takes without checking with the doctor.

What are some things I need to know or do while my child takes this drug?

All products:

  • Tell dentists, surgeons, and other doctors that your child is using this drug.
  • This drug may affect certain lab tests. Be sure the doctor and lab workers know your child takes this drug.
  • Call the doctor if your child has throat pain, chest pain, very bad belly pain, trouble swallowing, or signs of a bleeding ulcer like black, tarry, or bloody stools, throwing up blood, or throw up that looks like coffee grounds. These may be signs of a worse health problem.
  • Low magnesium levels have rarely happened in people taking drugs like this one for at least 3 months. Most of the time, this has happened after 1 year of care. Your child will need to have their blood work checked if they will be taking this drug for a long time or if they take certain other drugs like digoxin or water pills. Talk with the doctor.
  • Long-term treatment (for instance longer than 3 years) with drugs like this one has rarely caused low vitamin B-12 levels. Talk with the doctor.
  • This drug may raise the chance of hip, spine, and wrist fractures in people with weak bones (osteoporosis). The chance may be higher if this drug is taken in high doses or for longer than a year. Talk with the doctor.
  • Use care if your child may have a risk for weak bones (alcohol use, cigarette smoking, other family members with brittle bones, taking drugs to treat seizures, taking steroids).

If your child is pregnant or breast-feeding a baby:

  • Talk with the doctor if your child is pregnant, becomes pregnant, or is breast-feeding a baby. You will need to talk about the benefits and risks of using this drug.

Nexium 24HR:

  • It may take a few days to see the full effect.
  • Call the doctor before giving this drug to a child younger than 18 years of age.

What are some side effects that I need to call my child’s doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child’s doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:

All products:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of low magnesium levels like mood changes, muscle pain or weakness, muscle cramps or spasms, seizures, shakiness, not hungry, very bad upset stomach or throwing up, or a heartbeat that does not feel normal.
  • Signs of kidney problems like unable to pass urine, change in the amount of urine passed, blood in the urine, or a big weight gain.
  • Very bad dizziness or passing out.
  • Very bad belly pain.
  • Shortness of breath.
  • A big weight loss.
  • Bone pain.
  • Fever or chills.
  • Sore throat.
  • This drug may raise the chance of a very bad type of loose stools (diarrhea). Call the doctor right away if your child has stomach pain or cramps, very loose or watery stools, or bloody stools. Do not try to treat loose stools without first checking with the doctor.
  • A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if your child has signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in the mouth, throat, nose, or eyes.

Shot:

  • Irritation where the shot is given.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child’s doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away:
  • Headache.
  • Feeling sleepy.
  • Belly pain.
  • Loose stools (diarrhea).
  • Hard stools (constipation).
  • Gas.
  • Dry mouth.
  • Upset stomach.
These are not all of the side effects that may occur. If you have questions about side effects, call your child’s doctor. Call your child’s doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best given?

Give this drug as ordered by your child’s doctor. Read all information given to you. Follow all instructions closely.

All products:

  • Give as you have been told, even if your child feels well.
  • Ask the doctor before you give your child antacids with this drug.

Nexium 24HR:

  • Give on an empty stomach before breakfast.
  • Swallow whole. Do not chew, break, or crush.
  • Give this drug with a full glass of water.
  • Do not use for more than 14 days or more often than every 4 months unless told to do so by the doctor.

All other oral products:

  • Give 1 hour before the first meal of the day.

Capsule:

  • Have your child swallow capsule whole. Do not let your child chew, break, or crush.
  • You may sprinkle contents of capsule on applesauce. Have your child swallow without chewing.
  • For children who have feeding tubes, you may make a liquid. Empty contents of capsule into a 60 mL syringe with 50 mL of water. Replace plunger and shake for 15 seconds. Flush feeding tube before and after this drug is taken.

Granules:

  • Mix 2.5 mg or 5 mg granules with 1 teaspoon (5 mL) and the 10 mg, 20 mg, or 40 mg granules with 1 tablespoon (15 mL) of water; let them sit for a few minutes. Mix and have your child drink.
  • Rinse cup with more water and have your child drink.
  • For children who have feeding tubes, you may make a liquid. Empty contents of packet into syringe with 5 or 15 mL of water. Replace plunger and shake. Let sit for a few minutes. Refill syringe with water, shake, and flush feeding tube.

Shot:

  • It is given as a shot into a vein.

What do I do if my child misses a dose?

All products:

  • Give a missed dose as soon as you think about it.
  • If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
  • Do not give 2 doses at the same time or extra doses.

Nexium 24HR:

  • Do not give more than 1 dose of this drug in the same day.

How do I store and/or throw out this drug?

All oral products:

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.

Shot:

  • This drug will be given to your child in a hospital or doctor’s office. You will not store it at home.

All products:

  • Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
  • Do not share your child’s drug with others and do not give anyone else’s drug to your child.
  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
  • Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Last Reviewed Date

2015-01-16

Copyright

Copyright © 2014 Clinical Drug Information, LLC and Lexi-Comp, Inc.

If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call 212-639-2000.

Esomeprazole
Printed on May 6, 2015, 5:48 pm [P-6133]