Alora; Climara; Delestrogen; Depo-Estradiol; Divigel; EC-RX Estradiol; Elestrin; Estrace; Estrasorb [DSC]; Estrogel; Evamist; Femring; Menostar; Minivelle; Vivelle-Dot
Climara; Depo-Estradiol; Divigel; Estrace; Estradot; EstroGel; Menostar; Oesclim; Sandoz-Estradiol Derm 100; Sandoz-Estradiol Derm 50; Sandoz-Estradiol Derm 75
- Estrogens may raise the chance of uterine cancer. Progestins may lower this chance. A warning sign for cancer of the uterus is vaginal bleeding. Report any vaginal bleeding to the doctor.
- Do not use estrogens to prevent heart disease or dementia. Using estrogens may raise the chances of having a heart attack, a stroke, breast cancer, ovarian cancer, a blood clot, or dementia.
- Use estrogens with or without progestin for the shortest time needed at the lowest useful dose.
Tablets, injection, and patch:
- It is used to add estrogen to the body when the ovaries have been taken out or do not work the right way.
- It may be given to your child for other reasons. Talk with the doctor.
Emulsion, gel, spray, and vaginal ring:
- If your child has been given this form of this drug, talk with the doctor for information about the benefits and risks. Talk with the doctor if you have questions or concerns about giving this drug to your child.
- If your child has an allergy to this drug or any part of this drug.
- If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If your child has ever had a very bad or life-threatening reaction called angioedema. Signs may be swelling of the hands, face, lips, eyes, tongue, or throat; trouble breathing; trouble swallowing; unusual hoarseness.
- If your child has had any of these health problems: Bleeding disorder, blood clots, a higher risk of having a blood clot, breast cancer, liver problems or liver tumor, heart attack, stroke, tumor where estrogen makes it grow, or vaginal bleeding where the cause is not known.
- If your child has eyesight problems like loss of eyesight from blood vessel problems in the eye.
- If your child has thickening of the endometrium (lining of the uterus).
If your child is pregnant:
- Do not give this drug to your child if she is pregnant.
- Tell all of your child’s health care providers that your child is taking this drug. This includes your child’s doctors, nurses, pharmacists, and dentists.
- This drug may raise the chance of blood clots, a stroke, or a heart attack. Talk with the doctor.
- Talk with the doctor if your child will need to be still for long periods of time like long trips, bedrest after surgery, or illness. Not moving for long periods may raise the chance of blood clots.
- If your child is allergic to tartrazine, talk with your child’s doctor. Some products have tartrazine.
- If your child has high blood sugar (diabetes), you will need to watch his/her blood sugar closely.
- High blood pressure has happened with drugs like this one. Have your child’s blood pressure checked as you have been told by the doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Your child may need to have a bone density test. Talk with the doctor.
- Be sure that your child has regular breast exams and gynecology check-ups. The doctor will tell you how often your child needs to have these. Your child will also need to do breast self-exams as the doctor has told you. Talk with the doctor.
- This drug may cause dark patches of skin on your child’s face. Avoid lots of sun, sunlamps, and tanning beds. Use sunscreen and dress your child in clothing and eyewear that protects him/her from the sun.
- This drug may affect certain lab tests. Tell all of your child’s health care providers and lab workers that your child takes this drug.
- Be sure your child does not smoke. Smoking raises the chance of heart disease. Talk with the doctor.
- Alcohol may interact with this drug. Be sure your child does not drink alcohol.
- If your child drinks grapefruit juice or eats grapefruit often, talk with your child’s doctor.
- This drug may affect growth in children and teens in some cases. They may need regular growth checks. Talk with the doctor.
If your child is breast-feeding a baby:
- Tell the doctor if your child is breast-feeding a baby. You will need to talk about any risks to the baby.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Very upset stomach or throwing up.
- Chest pain or pressure.
- Shortness of breath.
- Coughing up blood.
- Swelling, warmth, numbness, change of color, or pain in a leg or arm.
- Very bad headache.
- Very bad dizziness or passing out.
- Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
- Very bad belly pain.
- Back pain.
- Bulging eyes.
- Change in how contact lenses feel in the eyes.
- Loss of eyesight.
- Change in eyesight.
- A lump in the breast, breast soreness, or nipple discharge.
- Breast pain.
- Vaginal itching or discharge.
- Vaginal bleeding that is not normal.
- Low mood (depression).
- Mood changes.
- Memory problems or loss.
- Not able to pass urine or change in how much urine is passed.
- Pain when passing urine.
- Very bad irritation where this drug is used.
- Hair loss.
- Upset stomach or throwing up.
- Enlarged breasts.
- Breast soreness.
- Vaginal bleeding or spotting.
If your child has menstrual periods:
- Painful periods.
- Irritation where this drug is used.
- Irritation where the shot is given.
- It is given as a shot into a muscle.
- If you will be giving your child the shot, your child’s doctor or nurse will teach you how to give the shot.
- Follow how to give this drug as you have been told by your child’s doctor or read the package insert.
- Do not use if the solution is cloudy, leaking, or has particles.
- This drug is colorless to a faint yellow. Do not use if the solution changes color.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
- Give this drug at the same time of day.
- There may be days when your child will not take this drug.
- Give this drug with or without food. Give with food if it causes an upset stomach.
- Put patch on clean, dry, healthy skin. Move the site with each new patch.
- Put patch on a site without hair.
- Do not place on breast. Place below waistline.
- Do not put the patch on the waistline.
- Do not use patches that are cut or do not look right.
- If the patch falls off, put a new one on.
- Do not put on more than 1 patch at a time.
- Call your child’s doctor to find out what to do.
- Give a missed dose as soon as you think about it.
- If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
- Do not give 2 doses at the same time or extra doses.
- Put on a missed patch as soon as you think about it after taking off the old one.
- If you need to store this drug at home, talk with your child’s doctor, nurse, or pharmacist about how to store it.
All other products:
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- After you take off a skin patch, be sure to fold the sticky sides of the patch to each other.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
- Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.