Adult Medication

Brand Names: US

Granisol [DSC]; Sancuso; Sustol

Brand Names: Canada

Granisetron Hydrochloride Injection; Granisetron Hydrochloride Injection SDZ; Nat-Granisetron

What is this drug used for?

  • It is used to prevent upset stomach and throwing up.
  • It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take this drug?

All products:

  • If you have an allergy to granisetron or any other part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

Long-acting injection:

  • If you have kidney problems.
This drug may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

All products:

  • Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

Skin patch:

  • Avoid using a heating pad or other heating devices on the treated area.
  • Avoid sun, sunlamps, and tanning beds. This drug may not work as well or may cause skin irritation. Keep the patch covered with clothing. Keep the skin where the patch was used covered for 10 days after you take it off. Talk with the doctor.

Long-acting injection:

  • It is common to have injection site reactions with this drug. Some injection site reactions may happen up to 2 weeks or more after getting this drug. Some of these reactions may be very bad and need treatment. Talk with your doctor.
  • Allergic reactions may happen up to 7 days or more after getting this drug. Talk with your doctor.

Short-acting injection:

  • Some products have benzyl alcohol. Do not give a product that has benzyl alcohol in it to a newborn. Talk with the doctor to see if this product has benzyl alcohol in it.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

All products:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Chest pain or pressure or a fast heartbeat.
  • A heartbeat that does not feel normal.
  • Very bad dizziness or passing out.
  • Shortness of breath.
  • Feeling very tired or weak.
  • Fever or chills.
  • Sore throat.
  • Trouble controlling body movements.
  • Belly pain.
  • Swelling of belly.
  • A very bad and sometimes deadly health problem called serotonin syndrome may happen. The risk may be greater if you take this drug with drugs for depression, migraines, or certain other drugs. Call your doctor right away if you have agitation; change in balance; confusion; hallucinations; fever; fast or abnormal heartbeat; flushing; muscle twitching or stiffness; seizures; shivering or shaking; sweating a lot; very bad diarrhea, upset stomach, or throwing up; or very bad headache.

Skin patch:

  • Very bad skin irritation.

Long-acting injection:

  • Injection site pain or tenderness that you need to take a pain drug for or that causes problems with daily living.
  • Area that feels hard or bruise at the injection site that does not go away.
  • Signs of infection at the injection site like redness, warmth of the skin, or fever.
  • Bleeding at the injection site that is very bad or lasts longer than 24 hours.
  • Constipation that may be very bad can happen with this drug. This can happen up to 7 days after getting this drug. Some people have had to go to the hospital to be treated for very bad constipation. Call your doctor right away if you have constipation or if it gets worse after you use this drug.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

Long-acting injection:

  • Heartburn.

All other products:

  • Hard stools (constipation).

All products:

  • Headache.
  • Feeling tired or weak.
  • Loose stools (diarrhea).
  • Dizziness.
  • Not able to sleep.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.

All oral products:

  • Take with or without food.

Liquid (solution):

  • Measure liquid doses carefully. Use the measuring device that comes with this drug. If there is none, ask the pharmacist for a device to measure this drug.

Skin patch:

  • Wash your hands before and after use.
  • Put on clean, dry, healthy skin on the upper arm.
  • Do not put on irritated skin.
  • Do not put on skin where you have just used creams, oils, lotions, powder, or other skin products. The patch may not stick as well.
  • Do not use patches that are cut or do not look right.
  • If the patch loosens, put tape ONLY on the edges of the patch to hold it in place.
  • You may bathe or shower while wearing the patch. Do not swim, use a hot tub, or sauna while wearing the patch.
  • After you take off a skin patch, be sure to fold the sticky sides of the patch to each other.

Long-acting injection:

  • It is given as a shot into the fatty part of the skin.
  • Do not use this drug more often than 1 time every 7 days.

Short-acting injection:

  • It is given as a shot into a vein.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

How do I store and/or throw out this drug?

All oral products and skin patch:

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.

All oral products:

  • Protect from light.

Skin patch:

  • Store patches in pouch until ready for use.

All injection products:

  • If you need to store this drug at home, talk with your doctor, nurse, or pharmacist about how to store it.

All products:

  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Last Reviewed Date



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