Ifex; Ifosfamide for Injection
- This drug may lower the ability of the bone marrow to make blood cells that the body needs. This can lead to needing a blood transfusion and very bad and sometimes deadly bleeding problems or infections. Tell the doctor right away if your child has signs of infection like fever, chills, or sore throat; any bruising or bleeding; or if your child feels very tired or weak.
- Have your child’s blood work checked often. Talk with your child’s doctor.
- This drug may cause blood in the urine and bladder pain. Talk with the doctor.
- This drug may cause kidney problems in some patients. Talk with the doctor.
- This drug may cause very bad and sometimes deadly brain problems, hallucinations, and confusion. Talk with the doctor.
- Your child will be closely watched by the doctor.
- It is used to treat cancer.
- If your child has an allergy to this drug or any part of this drug.
- If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If your child is not able to pass urine.
- Tell dentists, surgeons, and other doctors that your child is using this drug.
- Talk with the doctor before your child gets any vaccines. Use with this drug may either raise the chance of very bad infection or make the vaccine not work as well.
- If your child drinks grapefruit juice or eats grapefruit often, talk with your child’s doctor.
- Have your child avoid tasks or actions that call for alertness until you see how this drug affects your child. These are things like riding a bike, playing sports, or using items such as scissors, lawnmowers, electric scooters, toy cars, or motorized vehicles.
- Your child may bleed more easily. Make sure your child is careful and avoids injury. Be sure your child has a soft toothbrush.
- Your child may have more chance of getting infections. Avoid crowds and people with infections, colds, or flu.
- If your child has an upset stomach or loose stools (diarrhea), is throwing up, or is not hungry, talk with the doctor. There may be ways to lower these side effects.
- Alcohol may interact with this drug. Be sure your child does not drink alcohol.
- Talk with the doctor before giving your child other drugs and natural products that may slow your child’s actions.
- This drug may raise the chance of a very bad and sometimes deadly heart problem. Talk with the doctor.
- Other types of cancer may rarely happen later in life.
- Have your child pass urine often. Your child needs to empty his/her bladder often. Having your child drink lots of liquids will help.
- To help with mouth sores, have your child use a soft toothbrush or cotton swabs and rinse the mouth. Do not let your child use mouth rinses that have alcohol in them.
- This drug may cause your child to not be able to get pregnant later in life. Talk with the doctor.
- This drug may affect sperm in males. This may affect being able to father a child later in life. Talk with the doctor.
If your child is or may be sexually active:
- Have your child use birth control to prevent pregnancy while taking this drug.
- If your child is a male and has sex with a female who could get pregnant, they must prevent pregnancy during care and for 6 months after care ends. They must use birth control that can be trusted.
If your child is pregnant or breast-feeding a baby:
- This drug may cause harm to the unborn baby if your child takes it during pregnancy.
- Talk with the doctor if your child is pregnant, becomes pregnant, or is breast-feeding a baby. You will need to talk about the benefits and risks of using this drug.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Change in thinking clearly and with logic.
- Feeling very tired or weak.
- Any bruising or bleeding that is not normal.
- Very bad dizziness or passing out.
- Passing urine more often.
- Shortness of breath, a big weight gain, swelling in the arms or legs.
- Feeling sleepy.
- Change in eyesight, eye pain, or very bad eye irritation.
- Change in the way your child acts.
- Trouble controlling body movements, twitching, change in balance, trouble swallowing or speaking.
- A heartbeat that does not feel normal.
- Skin wound that will not heal.
- Hearing loss.
- Ringing in ears.
- Very bad and sometimes deadly lung problems have happened with this drug. Call the doctor right away if your child has lung or breathing problems like trouble breathing, shortness of breath, or a cough that is new or worse.
If your child has menstrual periods:
- For females, no period.
- Upset stomach or throwing up.
- Hair loss.
- It is given as an infusion into a vein over a period of time.
- Have your child drink lots of noncaffeine liquids every day unless told to drink less liquid by your child’s doctor.
- Call your child’s doctor to find out what to do.
- This drug will be given to your child in a hospital or doctor’s office. You will not store it at home.
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
- Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call 212-639-2000.
Ifosfamide©2016 Memorial Sloan Kettering Cancer Center - Generated on February 5, 2016