Apo-Indomethacin; Novo-Methacin; Pro-Indo; ratio-Indomethacin; Sandoz-Indomethacin
- This drug may raise the chance of very bad and sometimes deadly heart and blood vessel side effects like heart attack and stroke. The risk may be greater if you have heart disease or risks for heart disease. The risk may be greater with long-term use. Do not use this drug right before or after bypass heart surgery.
- This drug may raise the chance of very bad and sometimes deadly stomach or bowel side effects like ulcers or bleeding. The risk may be greater in older people. This may occur without warning signs. Talk with the doctor.
- It is used to treat arthritis.
- It is used to prevent gouty arthritis.
- It is used to treat ankylosing spondylitis.
- It is used to ease pain.
- It may be given to you for other reasons. Talk with the doctor.
- If you have an allergy to indomethacin or any other part of this drug.
- If you have an allergy to aspirin or NSAIDs.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have kidney disease.
- If you are more than 29 weeks pregnant.
- If you are taking any of these drugs: Aspirin, diflunisal, or triamterene.
- If you are taking any other NSAID.
- If you have had any of these health problems: Swelling of the rectum or anus, or recent rectal bleeding.
- Tell dentists, surgeons, and other doctors that you use this drug.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how this drug affects you.
- This drug may affect certain lab tests. Be sure your doctor and lab workers know you take this drug.
- Talk with your doctor before you drink alcohol.
- If you smoke, talk with your doctor.
- Have your blood work checked. Talk with your doctor.
- Have your blood pressure checked often if you are on this drug for a long time. Talk with your doctor.
- Do not take more than what your doctor told you to take. Taking more than you are told may raise your chance of very bad side effects.
- Do not take this drug for longer than you were told by your doctor.
- If you have asthma, talk with your doctor. You may be more sensitive to this drug.
- If you are taking aspirin to help prevent a heart attack, talk with your doctor.
- If you are 65 or older, use this drug with care. You could have more side effects.
- This drug may cause harm to the unborn baby if you take it while you are pregnant.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
- Shortness of breath, a big weight gain, swelling in the arms or legs.
- Chest pain or pressure or a fast heartbeat.
- Change in strength on 1 side is greater than the other, trouble speaking or thinking, change in balance, or blurred eyesight.
- Very bad headache.
- Very bad dizziness or passing out.
- Feeling very tired or weak.
- Change in eyesight.
- Ringing in ears.
- Mood changes.
- Low mood (depression).
- Very upset stomach or throwing up.
- Very bad belly pain.
- Very bad back pain.
- Bleeding from rectum or rectal pain.
- Not able to pass urine or change in how much urine is passed.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
- Belly pain or heartburn.
- Upset stomach or throwing up.
- Loose stools (diarrhea).
- Hard stools (constipation).
- Feeling sleepy.
- Rectal irritation.
All oral products:
- Take with food to prevent an upset stomach.
- Take with a full glass of water.
- Shake well before use.
- Measure liquid doses carefully. Use the measuring device that comes with this drug. If there is none, get an oral syringe, a dropper, a spoon, or a cup (only for older children) from your pharmacist.
- Swallow whole. Do not chew, break, or crush.
- Use suppository rectally.
- Wash your hands before and after use.
- If suppository is soft, chill in a refrigerator or run cold water over it.
- Take foil off the rectal suppository and put in, pointed end first. Do not handle too much.
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
All oral products:
- Store at room temperature. Do not refrigerate or freeze.
- Protect from light.
- Store in a dry place. Do not store in a bathroom.
- Store in original container.
- Store in a refrigerator. Do not freeze.
- Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call
Indomethacin©2015 Memorial Sloan Kettering Cancer Center - Generated on July 30, 2015