- It is used to treat a precancerous skin problem called actinic keratosis.
- If you have an allergy to ingenol or any other part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- Tell dentists, surgeons, and other doctors that you use this drug.
- If you get this drug in your eyes, it may cause eye problems like very bad eye pain, eyelid swelling or droop, or swelling around the eyes. Do not touch your eyes while using this drug. If you get this drug in your eyes, flush with water and call your doctor.
- Do not take more than what your doctor told you to take. Taking more than you are told may raise your chance of very bad side effects.
- Make sure sores near the area to be treated are healed before using this drug.
- Talk with your doctor before you use other drugs or products on your skin.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of skin infection like oozing, heat, swelling, redness, or pain.
- Very bad swelling.
- Very bad skin irritation.
- Skin irritation.
- Change in skin to hard and thick.
- Nose and throat irritation.
- Do not take this drug by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
- Wash your hands before and after use. Do not wash your hands after use if putting this on your hand.
- Use a new tube of gel each time you use this drug.
- Do not put on right after taking a shower or less than 2 hours before bedtime.
- Put a thin layer on the affected skin.
- Allow gel to dry for 15 minutes after using.
- Do not touch area where gel was put on your skin.
- Leave on the skin for 6 hours, then wash off.
- Avoid actions that may cause sweating for 6 hours after the gel is put on your skin.
- Do not cover with dressings.
- Do not get this drug on other parts of your body or on other people.
- Put on a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not put on 2 doses or extra doses.
- Store in a refrigerator. Do not freeze.
- Throw away any part not used after use.
- Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call
Ingenol Mebutate©2015 Memorial Sloan Kettering Cancer Center - Generated on September 1, 2015