Epivir; Epivir HBV
3TC; Apo-Lamivudine; Apo-Lamivudine HBV; Heptovir
- This drug may rarely cause swollen liver and an acid health problem in the blood. This may be deadly in some cases. The chance may be higher in women, in overweight people, and in people who have taken drugs like this one for a long time. Talk with your child’s doctor.
- Hepatitis B has gotten worse when this drug was stopped in some people with hepatitis B. Close follow-up for a few months is needed when therapy is stopped in people who have hepatitis B. Do not stop giving this drug to your child without calling your child’s doctor.
- There is more than 1 brand of this drug. One brand cannot safely be used for the other. Your child’s doctor will tell you about any needed change.
- Do not give your child this brand of this drug if your child has HIV infection. The dose of this brand is not enough and HIV may be harder to treat after taking it. HIV testing needs to be done before taking this brand. Talk with your child’s doctor.
- It is used to treat hepatitis B infection.
- It is used to treat HIV infection.
- If your child has an allergy to this drug or any part of this drug.
- If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If your child is taking another drug that has the same drug in it.
- If your child is taking emtricitabine.
- Tell dentists, surgeons, and other doctors that your child is using this drug.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This drug does not stop the spread of diseases like HIV or hepatitis that are passed through blood. Be sure needles and other things like toothbrushes or razors are not shared. Talk with the doctor.
- If giving to your child, the dose of this drug may need to be changed as your child’s weight changes. Have your child’s weight checked often. Talk with the doctor before changing your child’s dose.
If your child is or may be sexually active:
- This drug does not stop the spread of diseases like HIV or hepatitis that are passed through having sex. Be sure your child does not have any kind of sex without using a latex or polyurethane condom. Talk with the doctor.
If your child is pregnant:
- Tell the doctor if your child is pregnant or becomes pregnant. You will need to talk about the benefits and risks of your child using this drug while pregnant.
If your child is breast-feeding a baby:
- Tell the doctor if your child is breast-feeding a baby. You will need to talk about any risks to the baby.
- Be sure your child does not breast-feed a baby if she has HIV disease unless the doctor tells her to.
Treating HIV infection:
- If your child has HIV and hepatitis B, the hepatitis b virus can change while your child takes this drug. If this happens, the hepatitis B virus may be harder to treat. Talk with the doctor.
- Liver disease has gotten worse in people who have both HIV and hepatitis C when taking drugs like this one with some other drugs used to treat hepatitis C. Sometimes, this has been deadly. If your child has HIV and hepatitis C, talk with the doctor.
- Use this drug with care in children. They may have more side effects. Talk with the doctor.
- This drug is not a cure for HIV. Be sure your child stays under the care of the doctor.
Hepatitis B infection:
- Tell your child’s doctor if your child has never been on hepatitis care before.
- This drug is not a cure for hepatitis infection. Be sure your child stays under the care of the doctor.
For all patients taking this drug:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of too much lactic acid in the blood (lactic acidosis) like fast breathing, fast heartbeat, a heartbeat that does not feel normal, very bad upset stomach or throwing up, feeling very sleepy, shortness of breath, feeling very tired or weak, very bad dizziness, feeling cold, or muscle pain or cramps.
- Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
- A burning, numbness, or tingling feeling that is not normal.
- Mood changes.
- Change in body fat.
Treating HIV infection:
- This drug may help the immune system work. If your child has an infection that you did not know was there, it may show up when your child takes this drug. Tell your child’s doctor right away if you see any signs of infection like fever, sore throat, weakness, cough, or shortness of breath after your child starts this drug.
- Upset stomach or throwing up.
- Loose stools (diarrhea).
- Feeling tired or weak.
- Runny nose.
- Stuffy nose.
- Muscle pain.
- Not able to sleep.
- Nose and throat irritation.
- Ear irritation.
- To gain the most benefit, do not miss giving your child doses.
- Give as you have been told, even if your child feels well.
- Give this drug with or without food.
All liquid products:
- Measure liquid doses carefully. Use the measuring device that comes with this drug. If there is none, get an oral syringe, a dropper, a spoon, or a cup (only for older children) from your pharmacist.
- If your child has high blood sugar (diabetes), you will need to watch his/her blood sugar closely.
- Give a missed dose as soon as you think about it.
- If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
- Do not give 2 doses at the same time or extra doses.
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
- Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call 212-639-2000.
Lamivudine©2015 Memorial Sloan Kettering Cancer Center - Generated on November 30, 2015