Levonorgestrel (IUD)

Adult Medication

Brand Names: US

Kyleena; Liletta (52 MG); Mirena (52 MG); Skyla

Brand Names: Canada

Jaydess; Mirena

What is this drug used for?

  • It is used to prevent pregnancy.
  • It is used to treat heavy bleeding during monthly periods (menstruation).

What do I need to tell my doctor BEFORE I take this drug?

  • If you have an allergy to this drug or any part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are pregnant or may be pregnant. Do not use this drug if you are pregnant.
  • If you have an IUD (intrauterine device) in place.
  • If you have any of these health problems: Active liver disease, chlamydia or gonorrhea, endometritis after a birth, genital tract infection, infected abortion in the last 3 months, liver tumor, pelvic infection, uterine or cervical tumor or growth, uterine problems like uterine fibroids, or untreated cervicitis or vaginitis.
  • If you have unexplained vaginal bleeding.
  • If you have ever had any of these health problems: Breast cancer, cancer where hormones make it grow, or pelvic inflammatory disease.
  • If you have not started your period.
  • If you or your partner have sex with more than one person.
  • If your body is weak at fighting infections.
  • If you have ever abused drugs.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take this drug?

  • Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
  • Follow up with the doctor as you have been told.
  • This drug is not for use as emergency birth control. Talk with the doctor.
  • If you get pregnant while taking this drug, the chance of pregnancy outside of the uterus (ectopic pregnancy) may be raised. Talk with your doctor.
  • This drug does not stop the spread of diseases like HIV or hepatitis that are passed through blood or having sex. Do not have any kind of sex without using a latex or polyurethane condom. Do not share needles or other things like toothbrushes or razors. Talk with your doctor.
  • If you are having an MRI, talk with your doctor.
  • Life-threatening infection can happen within a few days after this drug was put in. Call your doctor right away if you have fever or pain where this drug was placed.
  • Very bad health problems and the need for surgery can happen if this drug goes through the uterus. This drug may also not prevent pregnancy if this happens. Talk with the doctor.
  • Vaginal bleeding, spotting, or cramps may happen for 3 to 6 months after this drug has been put in. If these signs do not go away or are very bad, call your doctor right away.
  • If you think this drug has come out, call your doctor. You may get pregnant if this drug comes out. Use another kind of birth control like a condom until you see your doctor.
  • This drug is not approved for use in women who are going through or have been through the change of life (menopause). Talk with your doctor.
  • If you think you may be pregnant while this drug is in place, call your doctor right away. Very bad and sometimes deadly health problems can happen when this drug is removed or if it is left in place during pregnancy. This includes loss of fertility, infections, and loss of the unborn baby. Talk with your doctor about the risks of getting pregnant while this drug is in place.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Weakness on 1 side of the body, trouble speaking or thinking, change in balance, or blurred eyesight.
  • Chest pain or pressure.
  • Dizziness.
  • Belly pain.
  • Pelvic pain.
  • Vaginal bleeding that is not normal.
  • Vaginal itching or discharge.
  • Fever or chills.
  • A lump in the breast or breast soreness.
  • Cannot feel string.
  • Device comes out.
  • Painful sex.
  • Very bad headache.
  • Any unexplained bruising or bleeding.
  • Yellow skin or eyes.
  • Mood changes.
  • Low mood (depression).
  • Genital sores.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
  • Pimples (acne).
  • Headache.
  • Upset stomach or throwing up.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best taken?

Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.
  • This drug will be given to you by a doctor.
  • Some pain, bleeding, or other reactions may happen when this drug is put in. These other reactions may include seizures, slow heartbeat, very bad dizziness, or passing out. Talk with your doctor.
  • If this drug is being removed and you do not want to get pregnant, talk with your doctor. You will need to use another kind of birth control like a condom the week before it is removed.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

How do I store and/or throw out this drug?

  • If you need to store this drug at home, talk with your doctor, nurse, or pharmacist about how to store it.

General drug facts

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else’s drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

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