This information from Lexicomp® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.
- It is used to treat spinal muscular atrophy.
- If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have liver disease.
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
For all patients taking this drug:
- Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
- Do not stop taking this drug without calling the doctor who ordered it for you.
- This drug may affect being able to father a child. Talk with the doctor.
- This drug may cause harm to an unborn baby. A pregnancy test will be done before you start this drug to show that you are NOT pregnant.
- If you may become pregnant, you must use birth control while taking this drug and for some time after the last dose. Ask your doctor how long to use birth control. If you get pregnant, call your doctor right away.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
- If your child’s weight changes, talk with the doctor. The dose of this drug may need to be changed.
- If the patient is an infant who is breast-feeding, give this drug after breast-feeding. Do not mix this drug with formula or milk.
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of a urinary tract infection (UTI) like blood in the urine, burning or pain when passing urine, feeling the need to pass urine often or right away, fever, lower stomach pain, or pelvic pain.
- Shortness of breath.
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Mild fever.
- Diarrhea or constipation.
- Throwing up.
- Mouth sores.
- Joint pain.
- Signs of a common cold.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.
Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take after a meal.
- Take this drug at the same time of day.
- Your pharmacist or other health care provider will need to mix this drug before you get it.
- Measure liquid doses carefully. Use the measuring device that comes with this drug.
- Take your dose within 5 minutes after you draw it into the oral syringe. Do not store this drug in the syringe. If not taken within 5 minutes, prepare a new dose.
- Drink water after you take this drug to make sure the dose is fully swallowed.
- Rinse the measuring device with water after each use.
- If you are not able to swallow the whole dose or throw up after taking a dose, do not repeat the dose. Take your next dose at your normal time.
- Those who have feeding tubes may use this drug. Use as you have been told. Flush the feeding tube after this drug is given.
- If you get this drug on the skin, wash it off right away with soap and water.
- If this drug gets in the eyes, rinse with cool water.
- Take a missed dose as soon as you think about it.
- If it has been 6 hours or more since the missed dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- Store in a refrigerator. Do not freeze. Throw away any unused part 64 days after this drug was mixed. Talk with your pharmacist if you are not sure when this is.
- If needed, this drug can be stored at room temperature up to 104°F (40°C) for a total of 5 days. This drug can be removed from, and returned to, a refrigerator. If this drug has been kept at room temperature for more than a total of 5 days, throw it away.
- Avoid temperatures higher than 104°F (40°C). Do not take this drug if it has been at a temperature higher than 104°F (40°C).
- Store in the original container to protect from light.
- Store upright with the cap on.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
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