- This drug can cause dizziness, loss of balance, ringing in the ears, anxiety, paranoia, low mood (depression), seizures, not thinking clearly or with logic, mood changes, changes in how you act, or hallucinations. These side effects may last for a few months or can be long-lasting and not go away even after the drug is stopped. Do not take this drug to prevent malaria if you have mental or mood problems. Call your doctor right away if you have any of these side effects.
- It is used to treat or prevent malaria.
- If you have an allergy to mefloquine or any other part of this drug.
- If you have an allergy to quinidine or quinine.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have ever had any of these health problems: Anxiety, low mood (depression), psychosis, any other mood problem, or seizures.
- If you are taking any of these drugs: Chloroquine, quinidine, or quinine.
- If you are taking any of these drugs: Halofantrine or ketoconazole. Do not take these drugs within 15 weeks of your last dose of this drug.
- If you have recently had a live vaccine
This is not a list of all drugs or health problems that interact with this drug.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
For all uses of this drug:
- Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how this drug affects you.
- Have patient safety card with you at all times.
- Have your blood work checked if you are on this drug for a long time. Talk with your doctor.
- Have an eye exam as you have been told by your doctor.
- This drug may raise the chance of seizures in some people, including people who have had seizures in the past. Talk to your doctor to see if you have a greater chance of seizures while taking this drug.
- This drug may affect how much of some other drugs are in your body. If you are taking other drugs, talk with your doctor. You may need to have your blood work checked more closely while taking this drug with your other drugs.
- Use with care in children. Talk with the doctor.
- Use birth control that you can trust to prevent pregnancy while taking this drug and for 3 months after care ends.
- If you get pregnant while taking this drug or within 3 months after your last dose, call your doctor right away.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
- Other measures are needed along with this drug including using screens, bed netting, insect repellent (10% to 35% DEET), and permethrin spray on clothing and nets. Avoid spraying most insect repellents on children. Lower evening and night-time outdoor activity.
- If you have a fever after leaving a malaria area, call your doctor right away.
- If you are a pregnant woman and traveling to a malaria infested place, talk to your doctor about the risks first.
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Chest pain or pressure or a fast heartbeat.
- Slow heartbeat.
- A heartbeat that does not feel normal.
- Very bad dizziness or passing out.
- Change in eyesight, eye pain, or very bad eye irritation.
- Not able to sleep.
- Some people taking this drug have killed themselves (suicide). It is not known if this drug was the reason for the suicides. Tell your doctor if you are thinking about killing yourself.
- Unsafe blood cell count problems have happened with this drug. This includes a type of anemia called aplastic anemia and a type of low white blood cell count. Report any fever or chills, shortness of breath, feeling very tired or weak, any unexplained bruising or bleeding, or purple “splotches” on your skin to your doctor right away.
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Upset stomach or throwing up.
- Belly pain.
- Not hungry.
- Muscle pain.
- Feeling tired or weak.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to your national health agency.
Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.
For all uses of this drug:
- Take this drug with the largest meal of the day.
- Do not take on an empty stomach.
- Take with a full glass of water.
- Tablet can be crushed and mixed with water, milk, or other liquid.
- To gain the most benefit, do not miss doses.
- Keep using this drug as you have been told by your doctor or other health care provider, even if you feel well.
- Talk with your doctor to find out what to do if you throw up after taking a dose of this drug.
- Use as you have been told to prevent malaria.
- If using to prevent malaria, start this drug before traveling to the high risk place.
- Most of the time, 1 dose of this drug is needed. If you miss the dose, take it as soon as you think about it with food. If you need to take more than 1 dose of this drug, follow what your doctor has told you to do.
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- If you miss a dose before leaving for your trip, call your doctor to find out what to do.
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.
© 2018 Wolters Kluwer Clinical Drug Information, Inc. and its affiliates and/or licensors. All rights reserved.