- This drug may have unsafe effects on the bone marrow. The bone marrow may not be able to make cells found in the blood as well as it used to for a few weeks. This may raise the chance of bleeding or infection. Talk with the doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Other types of cancer may rarely happen later in life.
- Allergic reactions may rarely occur.
- It is used to treat multiple myeloma.
- It is used to treat cancer of the ovary.
- It may be given to your child for other reasons. Talk with the doctor.
- If your child has an allergy to this drug or any part of this drug.
- If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
If your child is breast-feeding a baby:
- Be sure your child does not breast-feed a baby while taking this drug.
- Tell all of your child’s health care providers that your child is taking this drug. This includes your child’s doctors, nurses, pharmacists, and dentists.
- Your child may have more chance of getting infections. Have your child wash hands often. Avoid crowds and people with infections, colds, or flu.
- Your child may bleed more easily. Make sure your child is careful and avoids injury. Be sure your child has a soft toothbrush.
- Talk with the doctor before your child gets any vaccines. Use with this drug may either raise the chance of very bad infection or make the vaccine not work as well.
- If your child has an upset stomach or loose stools (diarrhea), is throwing up, or is not hungry, talk with the doctor. There may be ways to lower these side effects.
- To help with mouth sores, have your child use a soft toothbrush or cotton swabs and rinse the mouth. Do not let your child use mouth rinses that have alcohol in them.
- This drug may cause fertility problems. This may affect being able to have children later in life. Talk with the doctor.
If your child has menstrual periods:
- This drug may cause the ovaries to not work. This may also cause menstrual periods to stop. Talk with the doctor.
If your child is or may be sexually active:
- If your child is a male and has sex with a female who could get pregnant, they must prevent pregnancy during care and for some time after care ends. Talk with the doctor to see how long they must use birth control after your child stops this drug.
- If your child is a male and his sex partner gets pregnant while he takes this drug or within several months after his last dose, call the doctor right away.
- Have your child use birth control to prevent pregnancy during care and for some time after care ends. Talk with the doctor to see how long your child needs to use birth control after stopping this drug.
If your child is pregnant or breast-feeding a baby:
- This drug may cause harm to the unborn baby if your child takes it during pregnancy.
- If your child gets pregnant while taking this drug or within several months after her last dose, call the doctor right away.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, seizures, not hungry, or very bad upset stomach or throwing up.
- Very upset stomach or throwing up.
- Feeling very tired or weak.
- Pale skin.
- Any unexplained bruising or bleeding.
- Chest pain or pressure or a fast heartbeat.
- Dizziness or passing out.
- Shortness of breath.
- A big weight loss.
- For women, no period.
- A skin lump or growth.
- Blurred eyesight.
- Very bad and sometimes deadly lung problems have happened with this drug. Call the doctor right away if your child has lung or breathing problems like trouble breathing, shortness of breath, or a cough that is new or worse.
- This drug may cause tissue damage if the drug leaks from the vein. Tell your child’s nurse if your child has any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your child’s body.
- Upset stomach or throwing up.
- Stomach pain.
- Not hungry.
- Change in taste.
- Loose stools (diarrhea).
- Hard stools (constipation).
- Hair loss.
- Mouth irritation or mouth sores.
- Feeling tired or weak.
- Give on an empty stomach. Give 1 hour before or 2 hours after meals.
- Give this drug at the same time of day.
- You will need to take special care when handling this drug. Check with the doctor or pharmacist to see how to handle this drug.
- It is given as an infusion into a vein over a period of time.
- Other drugs may be given before this drug to help avoid side effects.
- Give a missed dose as soon as you think about it.
- If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
- Do not give 2 doses at the same time or extra doses.
- Call your doctor to find out what to do.
- Store in a refrigerator. Do not freeze.
- Protect from light.
- If you need to store this drug at home, talk with your child’s doctor, nurse, or pharmacist about how to store it.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
- Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.