Pediatric Medication

Brand Names: US

Apriso; Asacol HD; Asacol [DSC]; Canasa; Delzicol; Lialda; Pentasa; Rowasa; SfRowasa

Brand Names: Canada

Asacol; Asacol 800; Mesasal; Mezavant; Pentasa; Salofalk; Teva-5 ASA

What is this drug used for?

  • It is used to treat ulcerative colitis.
  • It is used to help keep ulcerative colitis flares from coming back.
  • It is used to treat mild to moderate disease at the far end of the colon.
  • It may be given to your child for other reasons. Talk with the doctor.

What do I need to tell the doctor BEFORE my child takes this drug?

  • If your child has an allergy to mesalamine, salicylates, sulfasalazine, or any part of this drug.
  • If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If your child has any of these health problems: Kidney disease or liver disease.
  • If your child has had a varicella vaccine in the past 6 weeks.
This is not a list of all drugs or health problems that interact with this drug.
Tell the doctor and pharmacist about all of your child’s drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for your child to take this drug with all of his/her drugs and health problems. Do not start, stop, or change the dose of any drug your child takes without checking with the doctor.

What are some things I need to know or do while my child takes this drug?

All products:

  • Tell all of your child’s health care providers that your child is taking this drug. This includes your child’s doctors, nurses, pharmacists, and dentists.
  • Have your child avoid tasks or actions that call for alertness until you see how this drug affects your child. These are things like riding a bike, playing sports, or using items such as scissors, lawnmowers, electric scooters, toy cars, or motorized vehicles.
  • Have your child’s blood work checked often. Talk with your child’s doctor.
  • This drug may affect certain lab tests. Tell all of your child’s health care providers and lab workers that your child takes this drug.
  • Do not give to children and teenagers who have or are getting better from flu signs, chickenpox, or other viral infections due to the chance of Reye’s syndrome. Reye’s syndrome causes very bad problems to the brain and liver.
  • Use with care in children. Talk with the doctor.
  • Your child may get sunburned more easily. Avoid lots of sun, sunlamps, and tanning beds. Use sunscreen and dress your child in clothing and eyewear that protects him/her from the sun.
  • Some males have had sperm problems while taking this drug. This may affect being able to father a child. This may go back to normal after the drug is stopped. Talk with the doctor.

If your child is pregnant or breast-feeding a baby:

  • Talk with the doctor if your child is pregnant, becomes pregnant, or is breast-feeding a baby. You will need to talk about the benefits and risks of using this drug.

All oral products:

  • You may see parts of this drug in your stool. If this happens a lot, talk with your doctor.

Long-acting capsules (Apriso):

  • If your child has phenylketonuria (PKU), talk with your child’s doctor. Some products have phenylalanine.
  • Do not give your child antacids at the same time as this drug. Talk with the doctor.

All rectal products:

  • This drug may stain fabric, flooring, painted surfaces, marble, granite, vinyl, and enamel.
  • If your child is allergic to sulfites, talk with your child’s doctor. Some products have sulfites in them.

What are some side effects that I need to call my child’s doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child’s doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
  • Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
  • Chest pain or pressure.
  • Throwing up blood or throw up that looks like coffee grounds.
  • A burning, numbness, or tingling feeling that is not normal.
  • Feeling confused.
  • A fast heartbeat.
  • A heartbeat that does not feel normal.
  • Fever or chills.
  • Very bad headache.
  • Very bad dizziness.
  • Very bad back pain.
  • Shortness of breath, a big weight gain, swelling in the arms or legs.
  • Any unexplained bruising or bleeding.
  • Feeling very tired or weak.
  • Some people may have a reaction to this drug that looks like the signs of ulcerative colitis. Call the doctor right away if your child has very bad belly pain or cramps, bloody stools, fever, headache, or rash.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child’s doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away:

All products:

  • Belly pain or heartburn.
  • Upset stomach or throwing up.
  • Hard stools (constipation).
  • Loose stools (diarrhea).
  • Headache.
  • Dizziness.
  • Gas.
  • Runny nose.
  • Stuffy nose.
  • Sore throat.
  • Muscle or joint pain.
  • Back pain.
  • Feeling tired or weak.

All rectal products:

  • Rectal irritation.
These are not all of the side effects that may occur. If you have questions about side effects, call your child’s doctor. Call your child’s doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best given?

Give this drug as ordered by your child’s doctor. Read all information given to you. Follow all instructions closely.

All products:

  • Keep giving this drug to your child as you have been told by your child’s doctor or other health care provider, even if your child feels well.
  • To gain the most benefit, do not miss giving your child doses.

All oral products:

  • Give this drug with a full glass of water.


  • Some drugs may need to be given with food or on an empty stomach. For some drugs, it does not matter. Check with your pharmacist about how to give this drug to your child.
  • Have your child swallow whole. Do not let your child chew, break, or crush.
  • If your child has trouble swallowing, talk with the doctor.


  • Give this drug with or without food.

Long-acting capsules (Pentasa):

  • Have your child swallow whole. Do not let your child chew, break, or crush.
  • If your child cannot swallow this drug whole, you may sprinkle the contents on applesauce or yogurt. Have your child swallow the mixture right away without chewing.

Long-acting capsules (Delzicol):

  • Have your child swallow capsule whole. Do not let your child chew, break, or crush.
  • If your child cannot swallow this drug whole, you may open the capsules and have your child swallow the contents. Be sure your child swallows the contents and that none stay in the mouth. Have your child swallow the contents whole. Do not let your child chew, break, or crush.

All other capsule products:

  • Have your child swallow whole. Do not let your child chew, break, or crush.
  • If your child has trouble swallowing, talk with the doctor.

All rectal products:

  • Your child could be on both a tablet or capsule and a rectal product at the same time.

Rectal enema:

  • Use enema rectally.
  • Shake suspension well before use.
  • Have your child keep suspension in rectum as long as can.


  • Use suppository rectally.
  • Use at bedtime.
  • Wash your hands before and after use.
  • If suppository is soft, chill in a refrigerator or run cold water over it.
  • Take foil off the suppository and put in, pointed end first. Do not handle too much. Ask your child to try and keep the suppository in for 1 to 3 hours or longer if your child can. Do not cut or break the suppository.

What do I do if my child misses a dose?

  • Give a missed dose as soon as you think about it.
  • If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
  • Do not give 2 doses at the same time or extra doses.

How do I store and/or throw out this drug?

All oral products:

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Store in the original container. Do not take out the antimoisture cube or packet.

Rectal enema:

  • Store rectal suspension in foil until ready to use. Do not refrigerate.
  • Protect rectal suspension from heat.
  • Do not use if suspension changes color.


  • Store at room temperature or in a refrigerator. Do not freeze.
  • Protect from heat.
  • Store in a dry place. Do not store in a bathroom.

All products:

  • Protect from light.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
  • Do not share your child’s drug with others and do not give anyone else’s drug to your child.
  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
  • Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Last Reviewed Date



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