- It is used to treat hereditary tyrosinemia type 1 (HT-1).
- If your child has an allergy to this drug or any part of this drug.
- If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- Tell dentists, surgeons, and other doctors that your child is using this drug.
- Have your child’s blood work checked often. Talk with your child’s doctor.
- Get your child an eye exam as you have been told by the doctor.
- Nitisinone must be used with a special diet that is low in tyrosine and phenylalanine.
- Have your child follow the diet plan your child’s doctor told you about.
If your child is pregnant or breast-feeding a baby:
- Talk with the doctor if your child is pregnant, becomes pregnant, or is breast-feeding a baby. You will need to talk about the benefits and risks of using this drug.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Change in skin on hands or feet.
- Change in eyesight, eye pain, or very bad eye irritation.
- Feeling confused.
- Fever or chills.
- Sore throat.
- Any bruising or bleeding that is not normal.
- Give as you have been told, even if your child feels well.
- To gain the most benefit, do not miss giving your child doses.
- Give on an empty stomach. Give 1 hour before or 2 hours after meals.
- Capsules may be opened and contents mixed with food or liquid.
- Give a missed dose as soon as you think about it.
- If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
- Do not give 2 doses at the same time or extra doses.
- Store in a refrigerator. Do not freeze.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
- Do not share your child’s drug with others and do not give anyone else’s drug to your child.
- Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
- Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call 212-639-2000.
Nitisinone©2016 Memorial Sloan Kettering Cancer Center - Generated on May 3, 2016