Signifor; Signifor LAR
- It is used to treat Cushing’s disease.
- It is used to treat acromegaly.
- If you have an allergy to pasireotide or any other part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have any of these health problems: Low potassium or magnesium levels.
- If you have liver disease.
- Tell dentists, surgeons, and other doctors that you use this drug.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- You will need an ECG before starting this drug. You may also need to have an ECG while using this drug. Talk with your doctor.
- If you have high blood sugar (diabetes), talk with your doctor. This drug may raise blood sugar.
- Check your blood sugar as you have been told by your doctor.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of gallstones like sudden pain in the upper right belly area, right shoulder area, or between the shoulder blades; yellow skin or eyes; or fever with chills.
- Signs of low blood sugar like dizziness, headache, feeling sleepy, feeling weak, shaking, a fast heartbeat, confusion, hunger, or sweating.
- Signs of low sodium levels like headache, trouble focusing, memory problems, change in thinking clearly and with logic, weakness, seizures, or change in balance.
- A heartbeat that does not feel normal.
- Slow heartbeat.
- Very bad dizziness or passing out.
- Very bad headache.
- This drug may lower the amount of certain hormones in your body. Call your doctor right away if you have abnormal diarrhea, dizziness, feeling tired or weak, nausea, not hungry, passing out, throwing up, or weight loss.
- Muscle cramps.
- Swelling in the arms or legs.
- Swelling of belly.
- Belly pain.
- Feeling tired or weak.
- Upset stomach.
- Loose stools (diarrhea).
- Hair loss.
- Nose and throat irritation.
- Irritation where the shot is given.
- Not able to sleep.
- Flu-like signs.
- Muscle pain.
- Joint pain.
- It is given as a shot into the fatty part of the skin on the top of the thigh or the belly area.
- Your doctor may teach you how to give the shot.
- Follow how to use carefully.
- Wash your hands before and after use.
- Do not give into red or irritated skin.
- Move the site where you give the shot with each shot.
- Do not use if the solution is cloudy, leaking, or has particles.
- Do not use if solution changes color.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
- It is given as a shot into a muscle.
- Use a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not use 2 doses or extra doses.
- Call the doctor to find out what to do.
- Store at room temperature.
- Protect from light.
- Store in a dry place. Do not store in a bathroom.
- Throw away any part not used after use.
- This drug will be given to you in a hospital or doctor’s office. You will not store it at home.
- Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call
Pasireotide©2015 Memorial Sloan Kettering Cancer Center - Generated on August 31, 2015