Cuprimine; Depen Titratabs
- It is used to treat Wilson’s disease.
- It is used to get rid of a protein called cystine from the body.
- It is used to treat rheumatoid arthritis.
- It may be given to you for other reasons. Talk with the doctor.
- If you have an allergy to penicillamine or any other part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have had low blood cell counts while taking this drug in the past.
- If you are breast-feeding. Do not breast-feed while you take this drug.
- If you are taking any of these drugs: Drugs used to treat malaria, gold products, oxyphenbutazone, or phenylbutazone.
- If you are taking any drugs that can damage cells in your body. There are many drugs that can do this. Ask your doctor or pharmacist if you are not sure.
Rheumatoid arthritis patients:
- If you have ever had kidney problems.
- If you are pregnant or may be pregnant. Do not take this drug if you are pregnant.
- Tell dentists, surgeons, and other doctors that you use this drug.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Have your urine checked. Talk with your doctor.
- Take vitamin B6 (pyridoxine) as you were told by your doctor.
- Follow the diet and workout plan that your doctor told you about.
- You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
- This drug may lower the ability of your bone marrow to make blood cells that your body needs. This can lead to very bad and sometimes deadly bleeding problems or infections. Tell your doctor right away if you have signs of infection like fever, chills, or sore throat; any bruising or bleeding; or if you feel very tired or weak.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
- Deaths from certain diseases like aplastic anemia, Goodpasture’s syndrome, and myasthenia gravis have happened with this drug. Talk with your doctor.
- Take good care of your teeth. See a dentist often.
- If you are 65 or older, use this drug with care. You could have more side effects.
- Use birth control that you can trust to prevent pregnancy while taking this drug.
- This drug may cause harm to the unborn baby if you take it while you are pregnant.
- If you are a woman and you miss a period, have unprotected sex, or think that your birth control has not worked, call your doctor right away.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of kidney problems like unable to pass urine, change in the amount of urine passed, blood in the urine, or a big weight gain.
- Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
- Signs of lupus like a rash on the cheeks or other body parts, sunburn easy, muscle or joint pain, chest pain or shortness of breath, or swelling in the arms or legs.
- Feeling very tired or weak.
- Any skin change.
- Swollen gland.
- Shortness of breath.
- Muscle pain or weakness.
- A burning, numbness, or tingling feeling that is not normal.
- Mood changes.
- Shakiness, trouble moving around, or stiffness.
- Joint pain.
- Change in eyesight.
- Back pain, belly pain, or blood in the urine. May be signs of a kidney stone.
- Upset stomach or throwing up.
- Loose stools (diarrhea).
- Change in taste.
- Not hungry.
- Belly pain.
- To gain the most benefit, do not miss doses.
- Take as you have been told, even if you feel well.
- Take on an empty stomach. Take 1 hour before or 2 hours after meals.
- Do not take other drugs within 1 hour of starting this drug. Talk with your doctor about how to take your other drugs with this drug.
- Do not take dairy products, bismuth (Pepto-Bismol®), calcium, iron, magnesium, zinc, multivitamins with minerals, colestipol, cholestyramine, didanosine, or antacids within 2 hours of this drug.
- Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
If you have any questions or concerns, talk with a member of your healthcare team. You can reach them Monday through Friday from 9:00 am to 5:00 pm at ____________________. After 5:00 pm, during the weekend, and on holidays, please call____________________. If there’s no number listed, or you’re not sure, call
Penicillamine©2015 Memorial Sloan Kettering Cancer Center - Generated on August 28, 2015