Compazine [DSC]; Compro
Apo-Prochlorperazine; Nu-Prochlor; PMS-Prochlorperazine; Sandoz-Prochlorperazine
- There is a higher chance of death in older adults who take this drug for mental problems caused by dementia. Most of the deaths were linked to heart disease or infection. This drug is not approved to treat mental problems caused by dementia.
- It is used to treat anxiety.
- It is used to treat upset stomach and throwing up.
- It is used to treat schizophrenia.
- It may be given to you for other reasons. Talk with the doctor.
For all patients taking this drug:
- If you have an allergy to prochlorperazine or any other part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have Reye’s syndrome.
- If you are very sleepy.
- If you have recently drunk a lot of alcohol or taken a big amount of drugs that may slow your actions like phenobarbital or some pain drugs like oxycodone.
- If your child has had recent surgery.
- If your child is younger than 2 years of age. Do not give this drug to a child younger than 2 years of age.
- If your child weighs less than 20 pounds (9 kilograms). Do not give to a child who weighs less than 20 pounds (9 kilograms).
- Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
- If you have an allergy to any type of nuts or seeds, talk with your doctor. Some products have nuts in them.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how this drug affects you.
- To lower the chance of feeling dizzy or passing out, rise slowly over a few minutes when sitting or lying down. Be careful climbing stairs.
- Low blood pressure has happened with drugs like this one. Sometimes, this has been deadly. Talk with the doctor.
- Avoid drinking alcohol while taking this drug.
- Talk with your doctor before you use other drugs and natural products that slow your actions.
- Be careful in hot weather or while being active. Drink lots of fluids to stop fluid loss.
- Low white blood cell counts have happened with drugs like this one. This may lead to a higher chance of getting an infection. Deadly infections have rarely happened. Tell your doctor if you have ever had a low white blood cell count. Call your doctor right away if you have signs of infection like fever, chills, or sore throat. Talk with your doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This drug may affect certain lab tests. Tell all of your health care providers and lab workers that you take this drug.
- Dizziness, sleepiness, and feeling less stable may happen with this drug. These may lead to falling. Broken bones or other health problems can happen from falling. Talk with the doctor.
- An unsafe heartbeat that is not normal (long QT on ECG) has happened with this drug. Sudden deaths have rarely happened in people taking this drug. Talk with the doctor.
- This drug may cause the results of some pregnancy tests to be wrong. Talk with the doctor.
- If you are 65 or older, use this drug with care. You could have more side effects.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
- Taking this drug in the third trimester of pregnancy may lead to muscle movements that cannot be controlled and withdrawal in the newborn. Talk with the doctor.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Trouble controlling body movements, twitching, change in balance, trouble swallowing or speaking.
- Very bad dizziness or passing out.
- Chest pain or pressure or a fast heartbeat.
- A heartbeat that does not feel normal.
- Feeling confused.
- Mood changes.
- Shakiness, trouble moving around, or stiffness.
- Swelling in the arms or legs.
- Change in eyesight.
- Any unexplained bruising or bleeding.
- Not able to pass urine.
- Feeling very tired or weak.
- Enlarged breasts.
- Nipple discharge.
- Change in sex ability.
- For women, no period.
- A very bad and sometimes deadly health problem called neuroleptic malignant syndrome (NMS) may happen. Call your doctor right away if you have any fever, muscle cramps or stiffness, dizziness, very bad headache, confusion, change in thinking, fast heartbeat, heartbeat that does not feel normal, or are sweating a lot.
- Some people who take this drug may get a very bad muscle problem called tardive dyskinesia. The risk may be greater in older adults, mainly women. The chance that this will happen or that it will never go away is greater in people who take this drug in higher doses or for a long time. Muscle problems may also occur after short-term use with low doses. Call your doctor right away if you have trouble controlling body movements or if you have muscle problems with your tongue, face, mouth, or jaw like tongue sticking out, puffing cheeks, mouth puckering, or chewing.
- Feeling nervous and excitable.
- Hard stools (constipation).
- Dry mouth.
- Feeling sleepy.
- Take with or without food. Take with food if it causes an upset stomach.
- Use suppository rectally.
- Wash your hands before and after use.
- If suppository is soft, chill in a refrigerator or run cold water over it.
- To use, take off foil wrapper and wet suppository with cold water. Use your finger to push the suppository well up into the rectum.
- It is given as a shot into a muscle or vein.
Oral products and suppository:
- If you take this drug on a regular basis, take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- Many times this drug is taken on an as needed basis. Do not take more often than told by the doctor.
- Call your doctor to find out what to do.
Oral products and suppository:
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Protect from light.
- If you need to store this drug at home, talk with your doctor, nurse, or pharmacist about how to store it.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.