Propranolol

Pediatric Medication

Brand Names: US

Hemangeol; Inderal LA; Inderal XL; InnoPran XL

Brand Names: Canada

Apo-Propranolol; Dom-Propranolol; Inderal LA; PMS-Propranolol; Propranolol Hydrochloride Injection, USP; Teva-Propranolol

Warning

Products other than Hemangeol:

  • Do not stop giving this drug to your child all of a sudden. If you do, chest pain that is worse and in some cases heart attack may occur. The chance may be higher if your child has certain types of heart disease. To avoid side effects, you will want to slowly stop this drug as ordered by the doctor. Call the doctor right away if your child has new or worse chest pain or if other heart problems happen.

What is this drug used for?

Hemangeol:

  • It is used to treat proliferating infantile hemangioma.

Products other than Hemangeol:

  • It is used to treat high blood pressure.
  • It may be given to your child for other reasons. Talk with the doctor.

What do I need to tell the doctor BEFORE my child takes this drug?

All products:

  • If your child has an allergy to this drug or any part of this drug.
  • If your child is allergic to any drugs like this one or any other drugs, foods, or other substances. Tell the doctor about the allergy and what signs your child had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

Hemangeol:

  • If your child was born premature and has not reached the corrected age of 5 weeks.
  • If your child weighs less than 4 ½ pounds (2 kilograms).
  • If your child has asthma or has had breathing problems.
  • If your child has any of these health problems: Certain heart problems, a slow heartbeat, or very low blood pressure.
  • If your child has high blood pressure caused by a tumor of the adrenal gland (pheochromocytoma).
  • If your child is at risk for low blood sugar, like if your child is throwing up or not able to take feedings.

Products other than Hemangeol:

  • If your child has any of these health problems: Asthma, bronchitis, or a slow heartbeat without a working pacemaker.
This is not a list of all drugs or health problems that interact with this drug.
Tell the doctor and pharmacist about all of your child’s drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for your child to take this drug with all of his/her drugs and health problems. Do not start, stop, or change the dose of any drug your child takes without checking with the doctor.

What are some things I need to know or do while my child takes this drug?

All products:

  • Tell all of your child’s health care providers that your child is taking this drug. This includes your child’s doctors, nurses, pharmacists, and dentists.
  • Have your child’s blood pressure and heart rate checked often. Talk with your child’s doctor.
  • This drug may hide the signs of low blood sugar. Talk with the doctor.
  • If your child has high blood sugar (diabetes), you will need to watch his/her blood sugar closely.
  • If your child has had a very bad allergic reaction, talk with the doctor. Your child may have a chance of an even worse reaction if your child comes into contact with what caused the allergy. If your child uses epinephrine to treat very bad allergic reactions, talk with the doctor. Epinephrine may not work as well while your child is taking this drug.

Hemangeol:

  • This drug may raise the chance of stroke in some children who have very bad problems with the blood vessels in their brain. The risk is higher in children with a large hemangioma that affects the face or head. Talk with the doctor.
  • If you are breast-feeding your child, tell the doctor about all the drugs you are taking. Certain drugs may pass to your child through breast milk and may interact with this drug.

All liquid products:

  • Make sure you have the right liquid; there is more than one strength.

Products other than Hemangeol:

  • Have your child avoid tasks or actions that call for alertness until you see how this drug affects your child. These are things like riding a bike, playing sports, or using items such as scissors, lawnmowers, electric scooters, toy cars, or motorized vehicles.
  • To lower the chance of feeling dizzy or passing out, have your child get up slowly over a few minutes when sitting or lying down. Have your child be extra careful climbing stairs.
  • This drug may affect certain lab tests. Tell all of your child’s health care providers and lab workers that your child takes this drug.
  • Alcohol may interact with this drug. Be sure your child does not drink alcohol.
  • If your child smokes, talk with the doctor.
  • If your child is taking warfarin, talk with the doctor. Your child may need to have blood work checked more closely while taking it with this drug.
  • If your child is taking this drug and has high blood pressure, talk with the doctor before giving OTC products that may raise blood pressure. These include cough or cold drugs, diet pills, stimulants, ibuprofen or like products, and some natural products or aids.

If your child is pregnant or breast-feeding a baby:

  • Talk with the doctor if your child is pregnant, becomes pregnant, or is breast-feeding a baby. You will need to talk about the benefits and risks of using this drug.

What are some side effects that I need to call my child’s doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your child’s doctor or get medical help right away if your child has any of the following signs or symptoms that may be related to a very bad side effect:

All products:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Very bad dizziness or passing out.
  • Shortness of breath, a big weight gain, swelling in the arms or legs.
  • Slow heartbeat.
  • A heartbeat that does not feel normal.
  • Feeling cold.

Hemangeol:

  • Feeling fussy.
  • Change in color of skin.
  • Fever or chills.
  • Wheezing or coughing.
  • Pale skin.
  • Feeling very tired or weak.
  • This drug may lower blood sugar levels. The chance is higher if your child is not taking feedings or is throwing up. Feed your child on a regular basis while giving this drug. Tell the doctor if your child has a poor appetite. If your child is not taking feedings due to an illness or throwing up, do not give this drug until your child is feeding normally again unless told to do so by the doctor. Call the doctor or get medical help right away if your child has signs of low blood sugar like pale, blue, or purple skin color; sweating; feeling fussy; crying that is not normal; fast heartbeat; a heartbeat that does not feel normal; poor feeding; low body temperature; sleeping more than normal; seizures; or breathing stops for a short time.

Products other than Hemangeol:

  • Signs of low blood sugar like dizziness, headache, feeling sleepy, feeling weak, shaking, a fast heartbeat, confusion, hunger, or sweating.
  • Chest pain that is new or worse.
  • Feeling confused.
  • Hallucinations (seeing or hearing things that are not there).
  • Memory problems or loss.
  • Mood changes.
  • A burning, numbness, or tingling feeling that is not normal.
  • Change in eyesight.
  • Any unexplained bruising or bleeding.
  • A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if your child has signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in the mouth, throat, nose, or eyes.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your child’s doctor or get medical help if any of these side effects or any other side effects bother your child or do not go away:

All products:

  • Loose stools (diarrhea).
  • Not able to sleep.
  • Throwing up.
  • Feeling sleepy.

Products other than Hemangeol:

  • Dizziness.
  • Hard stools (constipation).
  • Feeling tired or weak.
  • Upset stomach.
These are not all of the side effects that may occur. If you have questions about side effects, call your child’s doctor. Call your child’s doctor for medical advice about side effects.
You may report side effects to your national health agency.

How is this drug best given?

Give this drug as ordered by your child’s doctor. Read all information given to you. Follow all instructions closely.

Inderal XL and InnoPran XL:

  • Give this drug with or without food. Always give with food or always give on an empty stomach.

All other oral products:

  • Some drugs may need to be given with food or on an empty stomach. For some drugs, it does not matter. Check with your pharmacist about how to give this drug to your child.

All liquid products:

  • Measure liquid doses carefully. Use the measuring device that comes with this drug. If there is none, ask the pharmacist for a device to measure this drug.

Hemangeol:

  • Do not shake the solution.
  • Give this drug right into your child’s mouth. If needed, this drug may be mixed with a little bit of milk or fruit juice and given in a baby’s bottle.
  • Give this drug with or right after a feeding.
  • Give doses of this drug at least 9 hours apart.
  • If giving to your child, the dose of this drug may need to be changed as your child’s weight changes. Have your child’s weight checked often. Talk with the doctor before changing your child’s dose.
  • If your child spits up a dose or if you are not sure your child got all of the drug, do not give another dose. Wait until your child’s next dose to give again.

All long-acting products:

  • Have your child swallow whole. Do not let your child chew, break, or crush.

All oral products:

  • To gain the most benefit, do not miss giving your child doses.
  • Keep giving this drug to your child as you have been told by your child’s doctor or other health care provider, even if your child feels well.

Injection:

  • It is given as a shot into a vein.

What do I do if my child misses a dose?

All oral products:

  • Give a missed dose as soon as you think about it.
  • If it is close to the time for your child’s next dose, skip the missed dose and go back to your child’s normal time.
  • Do not give 2 doses at the same time or extra doses.

Injection:

  • Call your child’s doctor to find out what to do.

How do I store and/or throw out this drug?

All oral products:

  • Store at room temperature.
  • Protect from light.
  • Store in a dry place. Do not store in a bathroom.

All liquid products:

  • Do not freeze.

Hemangeol:

  • Throw away any part of the solution not used after 2 months.

Injection:

  • If you need to store this drug at home, talk with your child’s doctor, nurse, or pharmacist about how to store it.

All products:

  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

General drug facts

  • If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor.
  • Do not share your child’s drug with others and do not give anyone else’s drug to your child.
  • Keep a list of all your child’s drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your child’s doctor.
  • Talk with your child’s doctor before giving your child any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your child’s doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Consumer Information Use and Disclaimer

This information should not be used to decide whether or not to take this medicine or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Last Reviewed Date

2016-05-24

Copyright

© 2016 Wolters Kluwer Clinical Drug Information, Inc. and its affiliates and/or licensors. All rights reserved.