Recombinant Human TSH and Radioactive Iodine Treatment: 2-Week Regimen

This information describes the 2-week regimen for your recombinant human thyroid stimulating hormone (TSH) regimen. A regimen is a course of treatment.

Treatment with radioactive iodine helps lower the risk that thyroid cancer will come back. It’s also used to treat thyroid cancer that has spread.

Your nurse will give you more information about how to prepare and what to expect during and after your treatment.

Follow a Low-Iodine Diet

You will need to follow a low-iodine diet before your regimen. Your nurse will give you a resource called Low Iodine Diet that has more instructions.

Start following the low-iodine diet ___ days before day 1 of your regimen.

Drink at least 8 (8-ounce) glasses of decaffeinated liquids every day. The liquids should include water and other beverages listed in the low-iodine diet guidelines.

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Regimen Schedule

During the first week of your regimen, you will have blood tests, scans, and injections (shots) of recombinant human TSH. You’ll also receive your treatment. 

You may be admitted to the hospital for treatment. If you’re admitted, you will be discharged from the hospital when the amount of radioactivity in your body is low enough. If you’re not admitted, your radiation safety officer will give you instructions at the time of treatment.

During the second week of your regimen, you will have a post-treatment scan. A staff member in Nuclear Medicine will arrange this for you.

Week 1
May start Monday, Tuesday or Wednesday
Day 1
(2 to 3 hours)
• Blood tests
• Recombinant human TSH injection
Day 2
(30 to 60 minutes)
• Recombinant human TSH injection
• Diagnostic dose of radioactive iodine
Day 3
(6 to 8 hours)
• Scan
• Treatment dose of radioactive iodine
Week 2
Post-treatment scan
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