- Very bad and sometimes deadly side effects may happen if you take this drug with certain other drugs like some drugs that are used for a heartbeat that is not normal, sleep, or migraines. Be sure to talk to your doctor and pharmacist about all the drugs you take.
- It is used to treat HIV infection.
- If you have an allergy to ritonavir or any other part of this drug.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you take any of these drugs: Alfuzosin, amiodarone, avanafil, cisapride, dihydroergotamine, ergotamine, flecainide, lovastatin, meperidine, methylergonovine, oral midazolam, pimozide, propafenone, quinidine, rivaroxaban, salmeterol, simeprevir, simvastatin, St. John’s wort, or triazolam.
- If you are taking sildenafil to treat pulmonary arterial hypertension (PAH).
- If you take colchicine and have kidney or liver problems.
- Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
- This drug interacts with many other drugs. The chance of this drug’s side effects may be raised or how well this drug works may be lowered. The chance of the other drugs’ side effects may also be raised. This may include very bad, life-threatening, or deadly side effects. Check with your doctor and pharmacist to make sure that it is safe for you to take this drug with all of your other drugs (prescription or OTC, natural products, vitamins).
- If you have high blood sugar (diabetes), talk with your doctor. This drug may raise blood sugar.
- Check your blood sugar as you have been told by your doctor.
- Some people with hemophilia have had times of more bleeding when taking drugs like this one. If you have hemophilia, talk with your doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This drug is not a cure for HIV. Stay under the care of your doctor.
- This drug does not stop the spread of diseases like HIV or hepatitis that are passed through blood or having sex. Do not have any kind of sex without using a latex or polyurethane condom. Do not share needles or other things like toothbrushes or razors. Talk with your doctor.
- This drug may help the immune system work. If you have an infection that you did not know you had, it may show up when you take this drug. Tell your doctor right away if you notice any signs of infection like fever, sore throat, weakness, cough, or shortness of breath after you start this drug.
- If giving to your child, the dose of this drug may need to be changed as your child’s weight changes. Have your child’s weight checked often. Talk with the doctor before changing your child’s dose.
- Birth control pills and other hormone-based birth control may not work as well to prevent pregnancy. Use some other kind of birth control also like a condom when taking this drug.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
- Do not breast-feed if you have HIV disease unless your doctor tells you to.
- This drug has alcohol and propylene glycol in it. Preterm newborns may have a higher chance of very bad and sometimes deadly side effects caused by propylene glycol. If you have questions, talk with the doctor or pharmacist.
- Use with care in children younger than 6 months old. Talk with the doctor.
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
- Chest pain or pressure or a fast heartbeat.
- A heartbeat that does not feel normal.
- Dizziness or passing out.
- Very upset stomach or throwing up.
- Not able to pass urine or change in how much urine is passed.
- Low mood (depression).
- Muscle or joint pain.
- Shortness of breath.
- Any unexplained bruising or bleeding.
- Sweating a lot.
- Feeling very tired or weak.
- Change in eyesight.
- Change in body fat.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
- Very bad and sometimes deadly liver problems have happened with this drug. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Very bad and sometimes deadly pancreas problems (pancreatitis) have happened with this drug. Call your doctor right away if you have very bad stomach pain, very bad back pain, or very upset stomach or throwing up.
- Upset stomach or throwing up.
- Loose stools (diarrhea).
- Not hungry.
- Belly pain.
- Feeling tired or weak.
- Change in taste.
- Numbness or tingling in the hands or feet.
- Numbness or tingling around the mouth.
- To gain the most benefit, do not miss doses.
- Keep taking this drug as you have been told by your doctor or other health care provider, even if you feel well.
- Take with meals.
- Swallow whole. Do not chew, break, or crush.
- Shake well before use.
- Measure liquid doses carefully. Use the measuring device that comes with this drug. If there is none, ask the pharmacist for a device to measure this drug.
- You may take liquid alone or mix with a full glass (8 ounces/240 mL) of chocolate milk, Ensure®, or Advera® to make it taste better. Take this drug within 1 hour of mixing.
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- Store in the original container at room temperature or in a refrigerator. If stored at room temperature, throw away any part not used after 30 days.
- Do not freeze.
- Protect from light.
- Store solution in the original container at room temperature. Keep the cap tightly closed. Throw away when the date on the bottle has been reached.
- Store tablets in the original container at room temperature. Keep the cap tightly closed. Throw away when the date on bottle has been reached. If stored outside of the original container, throw away any part not used after 2 weeks.
- Protect from heat.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Check with your pharmacist about how to throw out unused drugs.
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else’s drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.